Three-Year Outcomes Following TAVR in Younger (<75 Years) Low-Surgical-Risk Severe Aortic Stenosis Patients.
Modine T, Tchétché D, Van Mieghem N, Deeb G, Chetcuti S, Yakubov S, Sorajja P, Gada H, Mumtaz M, Ramlawi B, Bajwa T, Crouch J, Teirstein P, Kleiman N, Iskander A, Bagur R, Chu M, Berthoumieu P, Sudre A, Adrichem R, Ito S, Huang J, Popma J, Forrest J, Reardon M. Three-Year Outcomes Following TAVR in Younger (<75 Years) Low-Surgical-Risk Severe Aortic Stenosis Patients. Circulation Cardiovascular Interventions 2024, e014018. PMID: 39421943, DOI: 10.1161/circinterventions.124.014018.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementSelf-expanding transcatheter aortic valve replacementLow-risk patientsPatients aged <Society of Thoracic Surgeons Predicted Risk of MortalityRandomized to TAVRRate of severe prosthesis-patient mismatchSupra-annularThoracic Surgeons Predicted Risk of MortalityEvolut Low Risk TrialIncidence of disabling strokePatients treated with transcatheter aortic valve replacementRate of valve thrombosisSevere prosthesis-patient mismatchPatients treated with surgeryDisabling strokeIncidence of pacemaker implantationSevere aortic stenosis patientsRates of all-cause mortalityProsthesis-patient mismatchAortic valve replacementSevere aortic stenosisAortic stenosis patientsPatients to treatmentAll-cause mortality3-Year Outcomes From the Evolut Low Risk TAVR Bicuspid Study
Zahr F, Ramlawi B, Reardon M, Deeb G, Yakubov S, Song H, Kleiman N, Chetcuti S, Gada H, Mumtaz M, Leung S, Merhi W, Rovin J, DeFrain M, Muppala M, Kauten J, Rajagopal V, Huang J, Ito S, Forrest J. 3-Year Outcomes From the Evolut Low Risk TAVR Bicuspid Study. JACC Cardiovascular Interventions 2024, 17: 1667-1675. PMID: 39048253, DOI: 10.1016/j.jcin.2024.05.017.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisBicuspid Aortic Valve DiseaseBioprosthesisFemaleHeart Valve DiseasesHeart Valve ProsthesisHemodynamicsHumansMaleMiddle AgedPostoperative ComplicationsProspective StudiesProsthesis DesignRecovery of FunctionRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementRates of all-cause mortalityAll-cause mortalityAortic stenosisThoracic Surgeons Predicted Risk of Mortality scoreThoracic Surgeons Predicted RiskSevere paravalvular aortic regurgitationBicuspid aortic valve anatomyRisk of Mortality scoreEchocardiographic core laboratoryLow-surgical risk patientsAortic valve anatomyKaplan-Meier ratesLow surgical riskClinical events committeeAortic valve replacementSevere aortic stenosisParavalvular aortic regurgitationPermanent pacemaker implantationBicuspid aortic stenosisFavorable hemodynamic performanceEvaluated 3 yearsAttempted implantEchocardiographic outcomesAortic regurgitationTranscatheter or Surgical Aortic Valve Replacement in Women With Small Annuli at Low or Intermediate Surgical Risk
Modine T, Forrest J, Van Mieghem N, Deeb G, Yakubov S, Ali W, Tchétché D, Lam K, Oh J, Huang J, Mehran R, Reardon M. Transcatheter or Surgical Aortic Valve Replacement in Women With Small Annuli at Low or Intermediate Surgical Risk. The American Journal Of Cardiology 2024, 223: 147-155. PMID: 38641189, DOI: 10.1016/j.amjcard.2024.04.013.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementAortic valve replacementIntermediate surgical riskValve replacementSurgical riskAortic stenosisTranscatheter aortic valve replacement groupImpact of transcatheter aortic valve replacementSurgical aortic valve replacementMid-term clinical outcomesPatient-prothesis mismatchSmall aortic annulusMidterm clinical outcomesSevere aortic stenosisSelf-expandingEffective orifice areaAll-cause mortalityEvaluated 2 yearsPost hoc analysisRandomized controlled trialsAortic annulusSurgical groupPrimary endpointHemodynamic outcomesClinical outcomes