Alleviative effect of andrographolide on alpha‐naphthylisothiocyanate‐induced cholestatic liver injury in rats
Khamphaya T, Piyachaturawat P, Weerachayaphorn J. Alleviative effect of andrographolide on alpha‐naphthylisothiocyanate‐induced cholestatic liver injury in rats. The FASEB Journal 2013, 27: 1161.2-1161.2. DOI: 10.1096/fasebj.27.1_supplement.1161.2.Peer-Reviewed Original ResearchLiver injuryMonocyte chemoattractant protein-1Severe liver inflammationCholestatic liver damageCholestatic liver injuryBile duct proliferationChemoattractant protein-1Tumor necrosis factorPotential therapeutic actionNF-kB signalingGamma-glutamyl transpeptidaseLiver inflammationSerum aminotransferasesLiver failureLiver diseaseDuct proliferationLiver damageHepatoprotective effectMajor active compoundNecrosis factorHepatic accumulationNF-kBAndrographolide pretreatmentANITBile acids