2023
A scoping review of multigenerational impacts of grandparental exposures on mental health in grandchildren
Xiao J, Jain A, Bellia G, Nyhan K, Liew Z. A scoping review of multigenerational impacts of grandparental exposures on mental health in grandchildren. Current Environmental Health Reports 2023, 10: 369-382. PMID: 38008881, DOI: 10.1007/s40572-023-00413-8.Peer-Reviewed Original ResearchMental healthGrandparental ageAdverse delivery outcomesPregnancy-related factorsUse of diethylstilbestrolNeurodevelopmental disordersCurrent epidemiological studiesAttention-deficit/hyperactivity disorderMental health outcomesMedication intakeDelivery outcomesEpidemiological studiesHealth StudyHealth outcomesPregnancyBiological markersLiterature searchRecent FindingsWeHyperactivity disorderOutcome phenotypesSocial environmental stressorsDisordersExposure assessmentOutcomesMultigenerational effects
2020
Association of Grandparental and Parental Age at Childbirth With Autism Spectrum Disorder in Children
Gao Y, Yu Y, Xiao J, Luo J, Zhang Y, Tian Y, Zhang J, Olsen J, Li J, Liew Z. Association of Grandparental and Parental Age at Childbirth With Autism Spectrum Disorder in Children. JAMA Network Open 2020, 3: e202868. PMID: 32293683, PMCID: PMC7160691, DOI: 10.1001/jamanetworkopen.2020.2868.Peer-Reviewed Original ResearchConceptsGrandparental ageAdvanced parental ageParental ageOdds ratioDanish national health registriesMaternal age 40 yearsMultigenerational cohortASD riskDanish Psychiatric Central RegisterAutism spectrum disorderNational health registriesAge 40 yearsAge 50 yearsPsychiatric Central RegisterRisk of ASDLogistic regression analysisPaternal grandmotherTime of birthCentral RegisterCohort studyHealth registriesMaternal ageSingleton childrenMAIN OUTCOMESpectrum disorder