2024
Noninvasive in vivo photoacoustic detection of malaria with Cytophone in Cameroon
Yadem A, Armstrong J, Sarimollaoglu M, Kiki Massa C, Ndifo J, Menyaev Y, Mbe A, Richards K, Wade M, Zeng Y, Chen R, Zhou Q, Meten E, Ntone R, Tchuedji Y, Ullah S, Galanzha E, Eteki L, Gonsu H, Biris A, Suen J, Boum Y, Zharov V, Parikh S. Noninvasive in vivo photoacoustic detection of malaria with Cytophone in Cameroon. Nature Communications 2024, 15: 9228. PMID: 39455558, PMCID: PMC11511992, DOI: 10.1038/s41467-024-53243-z.Peer-Reviewed Original ResearchConceptsClearance of parasitemiaDetection of malariaMalaria-infected red blood cellsDiagnosed symptomatic casesCross-sectional cohortUncomplicated malariaMalaria diagnosticsMalaria infectionRed blood cellsSymptomatic casesTarget antigenAsymptomatic reservoirCameroonian adultsFlow cytometer platformBlood samplesReservoir of infectionBlood cellsLack sensitivityLongitudinal cohortMolecular assaysMalariaIRBCPoint-of-careCohortQuantitative PCR
2022
Towards rainbow portable Cytophone with laser diodes for global disease diagnostics
Jawad H, Yadem A, Menyaev Y, Sarimollaoglu M, Armstrong J, Watanabe F, Biris A, Stumhofer J, Nedosekin D, Suen J, Parikh S, Zharov V. Towards rainbow portable Cytophone with laser diodes for global disease diagnostics. Scientific Reports 2022, 12: 8671. PMID: 35606373, PMCID: PMC9126638, DOI: 10.1038/s41598-022-11452-w.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsEarly Detection of CancerErythrocytesLasers, SemiconductorMalariaMelanomaMicePlasmodium falciparumPlasmodium yoeliiConceptsPlasmodium yoelii murine modelDetect infected cellsMalaria-infected erythrocytesDiagnosis of melanomaMalaria progressionSickle anemiaMurine modelDiagnosis of cancerMelanoma cellsEarly diagnosisCardiovascular disordersIn vivoEarly diagnosis of cancerInfected cellsIn vitroBlood backgroundDisease markersRed clotsMelanomaHemozoinMarkersSelectable markerBacteremiaCellsAnemia