2024
Impacts of resident physician unionization on house staff compensation
Tyagi S, Shah R, Huttler J, Kayani J, Ghovanloo M, Effraim P. Impacts of resident physician unionization on house staff compensation. PLOS ONE 2024, 19: e0308100. PMID: 39361626, PMCID: PMC11449312, DOI: 10.1371/journal.pone.0308100.Peer-Reviewed Original ResearchConceptsNon-union counterpartsPhysician unionsWorking long hoursUnion statusResidency training programsUnion programCost-of-livingLow wagesStaff compensationLong hoursTraining programSalaryInternal medicine residency training programsPhysicians-in-trainingRegional factorsDisbursementBenefit dataCross-sectional investigationMonetary benefitsUnionResident salariesCompensationCost-of-living differencesPGY-1Residency programsMyocardial Recovery in the Systemic Context: A Philosophic Shift for the Heart Failure Subspecialty to Optimize Patient Care
Kapoor A, Kayani J, Saad M, Lala A. Myocardial Recovery in the Systemic Context: A Philosophic Shift for the Heart Failure Subspecialty to Optimize Patient Care. Methodist DeBakey Cardiovascular Journal 2024, 20: 98-108. PMID: 39184157, PMCID: PMC11342849, DOI: 10.14797/mdcvj.1416.Peer-Reviewed Original ResearchConceptsDelivery of careImprove functional capacityPatient careHealthcare systemFunctional capacityHeart failure managementCareHeart failureAging populationFrequent hospitalizationsMedical optimizationIncreased prevalenceModern patientsHolistic definitionMortality rateAmbulatory heart failureSpectrum of diseasesPhilosophical shiftFailure managementClinical outcomesMyocardial recoverySystem contextHealthcareSubspecialtyPatientsNational trends in musculoskeletal urgent care centers: Improved Medicaid access from 2019 to 2023
Dlott C, O’Marr J, Jain S, Metcalfe T, Kayani J, Bahel A, Wiznia D. National trends in musculoskeletal urgent care centers: Improved Medicaid access from 2019 to 2023. Medicine 2024, 103: e38936. PMID: 39093793, PMCID: PMC11296439, DOI: 10.1097/md.0000000000038936.Peer-Reviewed Original Research
2023
Severe functional mitral regurgitation and cardiogenic shock after transcatheter aortic valve replacement.
Akinmolayemi O, McCreery C, Prandi F, Samtani R, Mehta A, Suleman U, Kapoor A, Kayani J, Gidwani U, Lerakis S, Dangas G. Severe functional mitral regurgitation and cardiogenic shock after transcatheter aortic valve replacement. Journal Of Invasive Cardiology 2023, 36 PMID: 38787923, DOI: 10.25270/jic/24.00119.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementAortic valve replacementValve replacementSevere functional mitral regurgitationSymptomatic severe aortic stenosisFunctional mitral regurgitationSevere aortic stenosisCoronary artery diseaseHeart catheterizationMitral regurgitationAortic stenosisCardiogenic shockArtery diseaseTranscatheter
2019
Adult bone marrow progenitors become decidual cells and contribute to embryo implantation and pregnancy
Tal R, Shaikh S, Pallavi P, Tal A, López-Giráldez F, Lyu F, Fang YY, Chinchanikar S, Liu Y, Kliman HJ, Alderman M, Pluchino N, Kayani J, Mamillapalli R, Krause DS, Taylor HS. Adult bone marrow progenitors become decidual cells and contribute to embryo implantation and pregnancy. PLOS Biology 2019, 17: e3000421. PMID: 31513564, PMCID: PMC6742226, DOI: 10.1371/journal.pbio.3000421.Peer-Reviewed Original ResearchConceptsBM transplantsDecidual cellsPregnancy lossMesenchymal stem cellsAdult bone marrow progenitorsDecidualization-related genesBone marrow progenitorsAdult bone marrowWT donorsPhysiologic contributionSuccessful pregnancyBMDC recruitmentStromal expansionImmune cellsEndometrial cellsDeficient miceUterine expressionUterine tissueDecidual stromaPregnancyBone marrowNonhematopoietic cellsBMDCsHemochorial placentaMarrow progenitors
2018
Severely impaired terminal erythroid differentiation as an independent prognostic marker in myelodysplastic syndromes
Ali AM, Huang Y, Pinheiro RF, Xue F, Hu J, Iverson N, Hoehn D, Coutinho D, Kayani J, Chernak B, Lane J, Hillyer C, Galili N, Jurcic J, Mohandas N, An X, Raza A. Severely impaired terminal erythroid differentiation as an independent prognostic marker in myelodysplastic syndromes. Blood Advances 2018, 2: 1393-1402. PMID: 29903708, PMCID: PMC6020814, DOI: 10.1182/bloodadvances.2018018440.Peer-Reviewed Original ResearchConceptsIndependent prognostic markerMyelodysplastic syndromeOverall survivalPrognostic markerMultivariable Cox proportional hazards regression analysisCox proportional hazards regression analysisPowerful independent prognostic markerInternational Prognostic Scoring SystemProportional hazards regression analysisMyeloid/erythroid ratioTerminal erythroid differentiationIPSS-R categoryPrognostic scoring systemHazards regression analysisWorse overall survivalPoor overall survivalBone marrow samplesSurface expressionMost patientsProportion of cellsErythroid ratioMarrow samplesErythroid differentiationSRSF2 mutationsMDS samples
2017
Bisphenol-A exposure in utero programs a sexually dimorphic estrogenic state of hepatic metabolic gene expression
Ilagan Y, Mamillapalli R, Goetz L, Kayani J, Taylor HS. Bisphenol-A exposure in utero programs a sexually dimorphic estrogenic state of hepatic metabolic gene expression. Reproductive Toxicology 2017, 71: 84-94. PMID: 28476547, DOI: 10.1016/j.reprotox.2017.05.001.Peer-Reviewed Original ResearchConceptsBPA exposureGene expressionAdult gene expressionFetal BPA exposureBisphenol A (BPA) exposureMetabolic gene expressionEstrogen receptor alphaExpression of genesBeta gene expressionEstrogenic stateEstrogen treatmentPregnant miceMetabolic disordersE2 stimulationReceptor alphaFetal developmentLipid metabolismDay 9Developmental programmingSexual dimorphismFemale offspringLiverObesityGenesAdult responses