2002
Genetic Differentiation in the African Malaria Vector, Anopheles gambiae s.s., and the Problem of Taxonomic Status
Gentile G, della Torre A, Maegga B, Powell J, Caccone A. Genetic Differentiation in the African Malaria Vector, Anopheles gambiae s.s., and the Problem of Taxonomic Status. Genetics 2002, 161: 1561-1578. PMID: 12196401, PMCID: PMC1462204, DOI: 10.1093/genetics/161.4.1561.Peer-Reviewed Original ResearchConceptsRDNA typesIntergenic spacerChromosomal formsNominal speciesSavanna chromosomal formsSingle panmictic unitSingle nominal speciesInsecticide resistance genesAreas of sympatryAnopheles gambiae complexDistinct sequencesGambiae s.African malaria vectorsA. gambiae s.Genetic differentiationITS allelesGenetic discontinuityGenetic isolationPanmictic unitTaxonomic statusChromosome armsGeographic rangeRDNA regionComplete linkage disequilibriumAutosomal inversions
1997
Synonymous substitution rates in Drosophila: Mitochondrial versus nuclear genes
Moriyama E, Powell J. Synonymous substitution rates in Drosophila: Mitochondrial versus nuclear genes. Journal Of Molecular Evolution 1997, 45: 378-391. PMID: 9321417, DOI: 10.1007/pl00006243.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell NucleusDNA, MitochondrialDrosophilaDrosophila melanogasterEvolution, MolecularGenes, InsectModels, GeneticMutationTime FactorsConceptsSynonymous substitution ratesHigher synonymous substitution ratesNuclear genesMitochondrial genesSubstitution ratesDivergence time estimatesBase composition biasNuclear genomeSynonymous ratesHeterogeneity of ratesRelated speciesCodon usageBase compositionComposition biasMutation rateGenesDrosophilaMtDNATime estimatesTurnover rateTransversionsGenomeSpeciesDivergenceSubstitution numberEvolution of codon usage bias in Drosophila
Powell J, Moriyama E. Evolution of codon usage bias in Drosophila. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 7784-7790. PMID: 9223264, PMCID: PMC33704, DOI: 10.1073/pnas.94.15.7784.Peer-Reviewed Original ResearchConceptsCodon usage biasHigher codon usage biasUsage biasBiased genesMutation biasSynonymous sitesCodon biasAmino acidsLow codon usage biasDrosophila genesDNA evolutionEffect of recombinationSmall geneIndividual amino acidsLong genesSynonymous substitutionsTRNA poolPreferred codonsSynonymous polymorphismWobble positionDrosophilaSame nucleotideSelection hypothesisGenesLines of evidence
1996
Evolution of the mitochondrial DNA control region in the Anopheles gambiae complex
Caccone A, Garcia B, Powell J. Evolution of the mitochondrial DNA control region in the Anopheles gambiae complex. Insect Molecular Biology 1996, 5: 51-59. PMID: 8630535, DOI: 10.1111/j.1365-2583.1996.tb00040.x.Peer-Reviewed Original ResearchConceptsAnopheles gambiae complexChromosomal inversionsControl regionAT-rich control regionMtDNA protein-coding genesMitochondrial DNA control regionA. gambiaeGambiae complexMtDNA gene flowA. arabiensisProtein-coding genesDNA control regionAT-rich regionGene flowMolecular treesEvolutionary positionPhylogenetic positionMitochondrial DNAA. melasSpeciesThird positionGambiaeArabiensisIntra-individual variationTrees