2022
The role of alcohol intake in the pharmacogenetics of treatment with clozapine
Monroy-Jaramillo N, Martínez-Magaña JJ, Pérez-Aldana BE, Ortega-Vázquez A, Montalvo-Ortiz J, López-López M. The role of alcohol intake in the pharmacogenetics of treatment with clozapine. Pharmacogenomics 2022, 23: 371-392. PMID: 35311547, DOI: 10.2217/pgs-2022-0006.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAdverse reactionsAlcohol intakeConcomitant useSevere adverse reactionsGood therapeutic effectPrecision medicine approachRefractory psychosisAtypical antipsychoticsInterindividual responseTherapeutic effectClozapineMedicine approachPharmacogenetic studiesSignificant riskIntakePatientsGenetic variantsPharmacogeneticsAntipsychoticsPsychosisCYP1A2Receptors
2021
The Role of 5-HT2B Receptor on Aggression and Drugs of Abuse
Montalvo-Ortiz J, Coccaro E. The Role of 5-HT2B Receptor on Aggression and Drugs of Abuse. The Receptors 2021, 35: 291-307. DOI: 10.1007/978-3-030-55920-5_17.ChaptersAggressive behaviorDrugs of abuseReceptor subtypesBrain regionsDifferent subtypesNormal levelsDrug abuseInhibitory effectSubstance useInfluence of substancesGenetic factorsReceptor familyReceptorsSubtypesGenetic variantsImpulsive behaviorHigher proportionAbuseViolent behaviorMonoaminesEnvironmental factorsBrainCocaineContext of aggression