2023
Male-specific, replicable and functional roles of genetic variants and cerebral gray matter volumes in ADHD: a gene-wide association study across KTN1 and a region-wide functional validation across brain
Luo X, Lin X, Ide J, Luo X, Zhang Y, Xu J, Wang L, Chen Y, Cheng W, Zheng J, Wang Z, Yu T, Taximaimaiti R, Jing X, Wang X, Cao Y, Tan Y, Li C. Male-specific, replicable and functional roles of genetic variants and cerebral gray matter volumes in ADHD: a gene-wide association study across KTN1 and a region-wide functional validation across brain. Child And Adolescent Psychiatry And Mental Health 2023, 17: 4. PMID: 36609385, PMCID: PMC9824933, DOI: 10.1186/s13034-022-00536-0.Peer-Reviewed Original ResearchGray matter volumeAttention deficit hyperactivity disorderTotal intracranial volumeSubcortical gray matter volumesMRNA expressionBasal gangliaEuropean cohortABCD cohortMatter volumeCerebral gray matter volumeRisk of ADHDPathogenesis of ADHDGene-wide association studyAmygdala gray matter volumeRegulatory effectsDeficit hyperactivity disorderBrain cohortSubcortical regionsBrain regionsIntracranial volumeCohortSubcortical structuresADHD risk allelesADHD riskHyperactivity disorder
2018
Problem Drinking, Alcohol Expectancy, and Thalamic Resting-State Functional Connectivity in Nondependent Adult Drinkers
Zhornitsky S, Ide J, Wang W, Chao H, Zhang S, Hu S, Krystal J, Li C. Problem Drinking, Alcohol Expectancy, and Thalamic Resting-State Functional Connectivity in Nondependent Adult Drinkers. Brain Connectivity 2018, 8: 487-502. PMID: 30198312, PMCID: PMC6207153, DOI: 10.1089/brain.2018.0633.Peer-Reviewed Original ResearchConceptsAlcohol Use Disorders Identification TestResting-state functional connectivityThalamic connectivityCaudate connectivityFrontal associationThalamic dysfunctionCaudate headProblem drinkingWhole-brain linear regressionAE scoreSubcortical structuresFunctional connectivityBilateral caudate headRight caudate headDisorders Identification TestSex differencesThalamic subdivisionsThalamic subregionsParietal associationAlcohol misuseThalamusWhite matter tractographyAUDIT scoresNondependent drinkersAlcohol expectancies