2017
The hypoxia-adenosine link during inflammation
Bowser J, Lee J, Yuan X, Eltzschig H. The hypoxia-adenosine link during inflammation. Journal Of Applied Physiology 2017, 123: 1303-1320. PMID: 28798196, PMCID: PMC5792095, DOI: 10.1152/japplphysiol.00101.2017.Peer-Reviewed Original ResearchConceptsHypoxia-inducible factorInflammatory diseasesAdenosine metabolismAcute lung injuryInflammatory bowel diseaseExtracellular adenosine metabolismFuture treatment approachesLung injuryBowel diseaseMyocardial injuryProinflammatory responseInflammatory conditionsTissue protectionTreatment approachesInflammationTissue conditionsDiseaseHypoxic conditionsDirect targetInjuryHypoxiaTissue integrityMetabolismPatients
2016
Prognostic value and their clinical implication of 89-gene signature in glioma
Shahid M, Cho K, Nguyen M, Choi T, Jo Y, Aryal S, Yoo J, Yun H, Lee J, Eun Y, Lee J, Kang I, Ha J, Yoon H, Kim S, Kim S. Prognostic value and their clinical implication of 89-gene signature in glioma. Oncotarget 2016, 7: 51237-51250. PMID: 27323413, PMCID: PMC5239472, DOI: 10.18632/oncotarget.9983.Peer-Reviewed Original ResearchConceptsPrognostic valueHistological classificationGene signatureIndependent prognostic factorAggressive primary tumorAccurate prognostic valueWorst prognostic groupIndividual therapeutic outcomesAdjuvant chemotherapyOverall survivalPrognostic factorsPrognostic groupsPrimary tumorSubset analysisTumor groupIndividual patientsGlioma prognosisPatientsTherapeutic outcomesClinical implicationsClinical useIDH1 mutationPrognosisMicroarray chipGliomas