2023
Long-term Safety and Tolerability of Repeated Treatments With OnabotulinumtoxinA in Children With Neurogenic Detrusor Overactivity
Franco I, Hoebeke P, Dobremez E, Titanji W, Geib T, Jenkins B, Yushmanova I, Austin P. Long-term Safety and Tolerability of Repeated Treatments With OnabotulinumtoxinA in Children With Neurogenic Detrusor Overactivity. Journal Of Urology 2023, 209: 774-784. PMID: 36655470, DOI: 10.1097/ju.0000000000003157.Peer-Reviewed Original ResearchMeSH KeywordsAdultBotulinum Toxins, Type AChildDouble-Blind MethodHumansTreatment OutcomeUrinary Bladder, NeurogenicUrinary Bladder, OveractiveUrinary Tract InfectionsConceptsTreatment-emergent adverse eventsNeurogenic detrusor overactivityUrinary tract infectionAdverse eventsSingle-treatment studyDetrusor overactivityTract infectionsSafety profileCommon treatment-emergent adverse eventsSerious treatment-emergent adverse eventsUrinary tract infection rateSimilar safety profileClean intermittent catheterizationNew safety concernsLong-term safetyAutonomic dysreflexiaIntermittent catheterizationMedian durationOnabotulinumtoxinA treatmentDistant spreadDose groupPediatric dataRepeat treatmentRepeated TreatmentPatients
2020
Response to commentary ‘Magnetic resonance image connectivity analysis provides evidence of central nervous system mode of action for parasacral transcutaneous electro neural stimulation - A pilot study'
Franco I. Response to commentary ‘Magnetic resonance image connectivity analysis provides evidence of central nervous system mode of action for parasacral transcutaneous electro neural stimulation - A pilot study'. Journal Of Pediatric Urology 2020, 16: 544. PMID: 32928661, DOI: 10.1016/j.jpurol.2020.08.017.Peer-Reviewed Original ResearchHumansMagnetic Resonance SpectroscopyNervous SystemPilot ProjectsTranscutaneous Electric Nerve StimulationUrinary Bladder, OveractiveMagnetic resonance image connectivity analysis provides evidence of central nervous system mode of action for parasacral transcutaneous electro neural stimulation - A pilot study
Netto JMB, Scheinost D, Onofrey JA, Franco I. Magnetic resonance image connectivity analysis provides evidence of central nervous system mode of action for parasacral transcutaneous electro neural stimulation - A pilot study. Journal Of Pediatric Urology 2020, 16: 536-542. PMID: 32873504, DOI: 10.1016/j.jpurol.2020.08.002.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainHumansMagnetic Resonance ImagingPilot ProjectsTranscutaneous Electric Nerve StimulationUrinary Bladder, OveractiveConceptsDorsal lateral prefrontal cortexAnterior cingulate cortexOveractive bladderFunctional connectivityPrefrontal cortexUrinary tract symptomsSacral nerve stimulatorCommon treatment modalityRight scapular regionACC functional connectivityResting-state conditionsMechanism of actionTract symptomsMotor thresholdCentral effectsACC connectivityNerve stimulatorSacral levelTreatment modalitiesFunctional connectivity dataMechanism of effectivenessAdult volunteersFrontal lobeSubcortical regionsCingulate cortex