2024
Management of the refractory nocturnal enuresis patient to desmopressin in a pediatric population: Desmopressin + oxybutynin vs. desmopressin + imipramine
Shain S, Gitlin J, Pantazis A, Fine R, Horowitz M, Friedman S, Zelkovic P, Dyer L, Schlussel R, Freyle J, Fang A, Sommer J, Franco I. Management of the refractory nocturnal enuresis patient to desmopressin in a pediatric population: Desmopressin + oxybutynin vs. desmopressin + imipramine. Journal Of Pediatric Urology 2024, 20: 603.e1-603.e8. PMID: 38871547, DOI: 10.1016/j.jpurol.2024.05.024.Peer-Reviewed Original ResearchVancouver Symptom ScoreInternational Children's Continence SocietyWet nightsDesmopressin treatmentCombination therapyResponse rateIntent-to-treat response rateCombination therapy of desmopressinFirst-line medical therapyEfficacy of adjunctive therapyGroup IMPComplete response rateTreated with desmopressinCohort of patientsContinence successPrescribed desmopressinEnuresis patientsMedical therapyNighttime drynessChart reviewAdjunctive therapyConclusion A combinationDesmopressinOxybutyninPediatric population
2017
Imipramine for refractory daytime incontinence in the pediatric population
Franco I, Arlen AM, Collett-Gardere T, Zelkovic PF. Imipramine for refractory daytime incontinence in the pediatric population. Journal Of Pediatric Urology 2017, 14: 58.e1-58.e5. PMID: 29100969, DOI: 10.1016/j.jpurol.2017.08.016.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild, PreschoolCohort StudiesDatabases, FactualDiurnal EnuresisDose-Response Relationship, DrugDrug Administration ScheduleFemaleHumansImipramineLower Urinary Tract SymptomsMaleQuality of LifeRetrospective StudiesRisk AssessmentSeverity of Illness IndexTreatment OutcomeUrinary IncontinenceUrodynamicsConceptsVancouver Symptom ScorePercutaneous tibial nerve stimulationTranscutaneous electrical nerve stimulationInternational Children's Continence SocietyLower urinary tractSide effectsAlpha blockersDaytime incontinenceNerve stimulationTreatment responseParasacral transcutaneous electrical nerve stimulationNon-selective alpha blockersPartial response groupTreat response rateSubsequent clinic visitsTibial nerve stimulationElectrical nerve stimulationAdditional treatment modalitiesComplete treatment responseHalf of childrenYears of ageBowel programRefractory incontinenceUrology referralClinic visits