2021
Next-Generation Sequencing for Pathogen Identification in Infected Foot Ulcers
Choi Y, Oda E, Waldman O, Sajda T, Beck C, Oh I. Next-Generation Sequencing for Pathogen Identification in Infected Foot Ulcers. Foot & Ankle Orthopaedics 2021, 6: 24730114211026933. PMID: 35097461, PMCID: PMC8702686, DOI: 10.1177/24730114211026933.Peer-Reviewed Original ResearchDiabetic foot ulcersFoot infectionsFoot ulcersNext-generation sequencingOrthopedic infectionsInfected diabetic foot ulcersFellowship-trained orthopedic footPostoperative antibiotic treatmentInfected foot ulcersStandard cultureConventional cultureWarrants further investigationManagement of footDFU patientsOrthopaedic FootOperative treatmentKnee amputationAntibiotic treatmentRay amputationOperative procedureAnkle surgeonsCommon pathogensAverage ageCommon microorganismsConcordance rate
2018
Tracking Anti-Staphylococcus aureus Antibodies Produced In Vivo and Ex Vivo during Foot Salvage Therapy for Diabetic Foot Infections Reveals Prognostic Insights and Evidence of Diversified Humoral Immunity
Oh I, Muthukrishnan G, Ninomiya MJ, Brodell JD, Smith BL, Lee CC, Gill SR, Beck CA, Schwarz EM, Daiss JL. Tracking Anti-Staphylococcus aureus Antibodies Produced In Vivo and Ex Vivo during Foot Salvage Therapy for Diabetic Foot Infections Reveals Prognostic Insights and Evidence of Diversified Humoral Immunity. Infection And Immunity 2018, 86: 10.1128/iai.00629-18. PMID: 30275008, PMCID: PMC6246899, DOI: 10.1128/iai.00629-18.Peer-Reviewed Original ResearchConceptsDiabetic foot infectionsIgG levelsDFI patientsSalvage therapyFoot infectionsCultured peripheral blood mononuclear cellsPeripheral blood mononuclear cellsBlood mononuclear cellsSimilar diagnostic potentialAggressive treatmentAntibody titersHumoral immunityMononuclear cellsPrognostic insightsPrognostic potentialCommon pathogensEtiologic agentMultivariate analysisClinical decisionEx vivoMultiplex immunoassayWound samplesInfectionSerumAureus antibody