2023
Does Coronary Plaque Morphology Matter Beyond Plaque Burden?
Lorenzatti D, Piña P, Csecs I, Schenone A, Gongora C, Garcia M, Blaha M, Budoff M, Williams M, Dey D, Berman D, Virani S, Slipczuk L. Does Coronary Plaque Morphology Matter Beyond Plaque Burden? Current Atherosclerosis Reports 2023, 25: 167-180. PMID: 36808390, DOI: 10.1007/s11883-023-01088-0.Peer-Reviewed Original ResearchConceptsCoronary computed tomography angiographyMedical therapyPlaque burdenResponse to medical therapyPlaque analysisCoronary plaquesAssessment of coronary plaquesHigh-risk phenotypePreventive medical therapyAdverse cardiovascular eventsCoronary plaque featuresRandomized controlled trialsPericoronary inflammationMyocardial infarction typeCardiovascular eventsDisease progressionRisk phenotypesCulprit plaquesControlled trialsPlaque characteristicsPlaque featuresTherapySummaryThe identificationTracking disease progressionInfarct type
2022
Potential clinical relevance of cardiac magnetic resonance to diagnose cardiac light chain amyloidosis
Dohy Z, Szabo L, Pozsonyi Z, Csecs I, Toth A, Suhai F, Czimbalmos C, Szucs A, Kiss A, Becker D, Merkely B, Vago H. Potential clinical relevance of cardiac magnetic resonance to diagnose cardiac light chain amyloidosis. PLOS ONE 2022, 17: e0269807. PMID: 35696411, PMCID: PMC9191721, DOI: 10.1371/journal.pone.0269807.Peer-Reviewed Original ResearchConceptsCardiac AL amyloidosisCardiac magnetic resonanceLate gadolinium enhancementAL amyloidosisOptimal diagnostic performanceHypertrophic cardiomyopathyDegree of left ventricular (LV) hypertrophyReduced global LV longitudinal strainDiagnostic performanceLeft ventricular (LV) hypertrophyPattern of late gadolinium enhancementGlobal LV longitudinal strainSubendocardial late gadolinium enhancementCardiac magnetic resonance examinationCardiac magnetic resonance parametersCardiac light-chain amyloidosisDifferential diagnosis of cardiomyopathyLV strain parametersCardiac transthyretin amyloidosisLV) hypertrophyLV longitudinal strainDiagnosis of cardiomyopathyLight chain amyloidosisCardiac light chainsPotential clinical relevanceAn Explainable Machine Learning Approach Reveals Prognostic Significance of Right Ventricular Dysfunction in Nonischemic Cardiomyopathy
Fahmy A, Csecs I, Arafati A, Assana S, Yankama T, Al-Otaibi T, Rodriguez J, Chen Y, Ngo L, Manning W, Kwong R, Nezafat R. An Explainable Machine Learning Approach Reveals Prognostic Significance of Right Ventricular Dysfunction in Nonischemic Cardiomyopathy. JACC Cardiovascular Imaging 2022, 15: 766-779. PMID: 35033500, DOI: 10.1016/j.jcmg.2021.11.029.Peer-Reviewed Original ResearchMeSH KeywordsCardiomyopathiesFemaleHumansMachine LearningPredictive Value of TestsPrognosisVentricular Dysfunction, RightConceptsNonischemic dilated cardiomyopathyBeth Israel Deaconess Medical CenterComposite endpointRight ventricular (RV) dysfunctionCardiovascular hospitalizationRisk prediction modelAdverse outcomesRisk markersMarker of adverse outcomeCardiac magnetic resonance markersRisk stratification of patientsRight ventricular dysfunctionRV ejection fractionMedical CenterFollow-up durationCardiac magnetic resonanceEnd-diastolic volumeStratification of patientsArea under the curveAll-cause deathHigh-risk thresholdVentricular dysfunctionEjection fractionNonischemic cardiomyopathyPrognostic significance
2021
Machine learning phenotyping of scarred myocardium from cine in hypertrophic cardiomyopathy
Mancio J, Pashakhanloo F, El-Rewaidy H, Jang J, Joshi G, Csecs I, Ngo L, Rowin E, Manning W, Maron M, Nezafat R. Machine learning phenotyping of scarred myocardium from cine in hypertrophic cardiomyopathy. European Heart Journal - Cardiovascular Imaging 2021, 23: 532-542. PMID: 33779725, PMCID: PMC9125682, DOI: 10.1093/ehjci/jeab056.Peer-Reviewed Original ResearchMeSH KeywordsCardiomyopathy, HypertrophicCicatrixContrast MediaFibrosisGadoliniumHumansMachine LearningMagnetic Resonance Imaging, CineMyocardiumPredictive Value of Tests
2019
The impact of sex, age and training on biventricular cardiac adaptation in healthy adult and adolescent athletes: Cardiac magnetic resonance imaging study
Csecs I, Czimbalmos C, Toth A, Dohy Z, Suhai I, Szabo L, Kovacs A, Lakatos B, Sydo N, Kheirkhahan M, Peritz D, Kiss O, Merkely B, Vago H. The impact of sex, age and training on biventricular cardiac adaptation in healthy adult and adolescent athletes: Cardiac magnetic resonance imaging study. European Journal Of Preventive Cardiology 2019, 27: 540-549. PMID: 31370686, DOI: 10.1177/2047487319866019.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PhysiologicalAdolescentAdultAge FactorsAthletesCardiomegaly, Exercise-InducedFemaleHeart VentriclesHumansMagnetic Resonance Imaging, CineMalePhysical Conditioning, HumanPredictive Value of TestsSex FactorsVentricular Function, LeftVentricular Function, RightVentricular RemodelingYoung AdultConceptsEnd-diastolic volume indexVentricular mass indexTraining hoursBody surface areaTraining volumeEndurance sportsCardiac adaptationImpact of sexVentricular massMass indexMale sexRight ventricular end-diastolic volume indexHigher training volumeVentricular volumeLeft ventricular end-diastolic volume indexCardiac magnetic resonance parametersWeekly training hoursRight ventricular ejection fractionVolume indexLeft ventricular mass indexRight ventricular mass indexCardiac magnetic resonance imagingRight/left ventricular ratioVentricular ejection fractionEnd-systolic volumeThe effect of contrast agents on left ventricular parameters calculated by a threshold-based software module: does it truly matter?
Szűcs A, Kiss A, Suhai F, Tóth A, Gregor Z, Horváth M, Czimbalmos C, Csécs I, Dohy Z, Szabó L, Merkely B, Vágó H. The effect of contrast agents on left ventricular parameters calculated by a threshold-based software module: does it truly matter? The International Journal Of Cardiovascular Imaging 2019, 35: 1683-1689. PMID: 31037474, PMCID: PMC6700040, DOI: 10.1007/s10554-019-01587-9.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiomechanical PhenomenaCase-Control StudiesContrast MediaFemaleHeart VentriclesHumansImage Interpretation, Computer-AssistedIsolated Noncompaction of the Ventricular MyocardiumMagnetic Resonance Imaging, CineMaleMeglumineMiddle AgedOrganometallic CompoundsPredictive Value of TestsProspective StudiesReproducibility of ResultsSoftwareStroke VolumeVentricular Function, LeftYoung AdultConceptsSteady-state free precessionGadobenate dimeglumineCine imagesLeft ventricular parametersAdministration of contrast agentContrast agentsLeft ventricular volumeBlood-myocardium contrastEffects of contrast agentsNoncompaction cardiomyopathyVentricular parametersTrabecular musclesVentricular volumeCardiac parametersPre-CASShort axisTime-saving techniqueGadobutrolTrabecular massH groupFree precessionTrabecularEffect of CALVmassCardiomyopathy
2018
Cardiac magnetic resonance based deformation imaging: role of feature tracking in athletes with suspected arrhythmogenic right ventricular cardiomyopathy
Czimbalmos C, Csecs I, Dohy Z, Toth A, Suhai F, Müssigbrodt A, Kiss O, Geller L, Merkely B, Vago H. Cardiac magnetic resonance based deformation imaging: role of feature tracking in athletes with suspected arrhythmogenic right ventricular cardiomyopathy. The International Journal Of Cardiovascular Imaging 2018, 35: 529-538. PMID: 30382474, PMCID: PMC6453871, DOI: 10.1007/s10554-018-1478-y.Peer-Reviewed Original ResearchMeSH KeywordsAdultArrhythmogenic Right Ventricular DysplasiaAthletesCardiomegaly, Exercise-InducedCase-Control StudiesDiagnosis, DifferentialFemaleHeart VentriclesHumansImage Interpretation, Computer-AssistedMagnetic Resonance Imaging, CineMaleMyocardial ContractionPredictive Value of TestsReproducibility of ResultsStroke VolumeVentricular Function, LeftVentricular Function, RightVentricular RemodelingConceptsArrhythmogenic right ventricular cardiomyopathyRV ejection fractionCardiac magnetic resonanceTask Force criteriaRV free wallRight ventricular cardiomyopathyCut-off valueAthlete's heartVentricular cardiomyopathyBalanced steady-state free precession cine imagesRight ventricular (RV) remodelingSuspected arrhythmogenic right ventricular cardiomyopathyDiagnosis of arrhythmogenic right ventricular cardiomyopathySteady-state free precession cine imagesFree wallHealthy athletesRV strain analysisRight ventricular volumesRV dilatationEjection fractionCine imagesVentricular volumeRegional strain analysisTrained athletesMagnetic resonance