Influence of Theophylline on Fetal Rat Lung Phosphatidylcholine Synthesis in vivo
Moya F, Gross I. Influence of Theophylline on Fetal Rat Lung Phosphatidylcholine Synthesis in vivo. Neonatology 1985, 8: 9-16. PMID: 3987490, DOI: 10.1159/000457017.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCholineFemaleFetusInjections, IntraperitonealKineticsLungPhosphatidylcholinesPregnancyRatsRats, Inbred StrainsTheophyllineConceptsSerum levelsFetal lung surfactant productionInfluence of theophyllineLung tissue concentrationsElevated serum levelsDoses of theophyllineLung surfactant productionPhosphatidylcholine synthesisMaternal ratioPregnant ratsIntraperitoneal administrationTissue concentrationsRate of incorporationSurfactant productionTheophyllineVivoFetusesRatsAdministrationDosesDelayed Pulmonary Maturation in the Fetus of the Streptozotocin-Diabetic Rat
Gewolb I, Rooney S, Barrett C, Ingleson L, Light D, Wilson C, Smith G, Gross I, Warshaw J. Delayed Pulmonary Maturation in the Fetus of the Streptozotocin-Diabetic Rat. Experimental Lung Research 1985, 8: 141-151. PMID: 4029093, DOI: 10.3109/01902148509057518.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDiabetes Mellitus, ExperimentalEmbryonic and Fetal DevelopmentFemaleLungPregnancyPregnancy in DiabeticsRatsRats, Inbred StrainsTime FactorsConceptsStreptozotocin-diabetic ratsDiabetic groupPulmonary maturationDay 21Lung developmentDelayed pulmonary maturationAlveolar lining cellsEffects of hyperglycemiaFetal lung developmentDays of gestationObserved developmental delayType II cellsControl lungsMaturational delayCholinephosphate cytidylyltransferase activityIntravenous injectionRat gestationDiabetic fetusesLining cellsDay 22Day 20FetusesActivity of enzymesDevelopmental delayDecreased number