ATP activates P2X receptors to mediate gap junctional coupling in the cochlea
Zhu Y, Zhao H. ATP activates P2X receptors to mediate gap junctional coupling in the cochlea. Biochemical And Biophysical Research Communications 2012, 426: 528-532. PMID: 22982314, PMCID: PMC3471361, DOI: 10.1016/j.bbrc.2012.08.119.Peer-Reviewed Original ResearchConceptsP2X receptorsGap junctional couplingCochlear gap junctionsP2Y receptor agonist UTPGap junctionsJunctional couplingP2X receptor antagonistMetabotropic purinergic receptorsReceptor agonist UTPStimulation of ATPPhysiological levelsReceptor antagonistP2Y receptorsPurinergic controlPurinergic receptorsBenzoylbenzoyl-ATPNoise stressReceptorsIonic homeostasisCochleaDisulfonic acidCritical roleIntercellular channelsATPCells