2004
Obesity and the Risk of New-Onset Atrial Fibrillation
Wang T, Parise H, Levy D, D’Agostino R, Wolf P, Vasan R, Benjamin E. Obesity and the Risk of New-Onset Atrial Fibrillation. JAMA 2004, 292: 2471-2477. PMID: 15562125, DOI: 10.1001/jama.292.20.2471.Peer-Reviewed Original ResearchConceptsBody mass indexNew-onset atrial fibrillationEchocardiographic left atrial diameterLeft atrial diameterAtrial fibrillationRisk factorsAtrial diameterBMI categoriesMass indexAF riskCommunity-based observational cohortNormal body mass indexAge-adjusted incidence ratesInterim myocardial infarctionCardiovascular risk factorsVentricular diastolic dysfunctionBaseline atrial fibrillationClinical risk factorsModifiable risk factorsInfluence of obesityDiastolic dysfunctionAtrial dilatationAtrial dimensionClinical confoundersHazard ratio
2003
Impact of Glucose Intolerance and Insulin Resistance on Cardiac Structure and Function
Rutter M, Parise H, Benjamin E, Levy D, Larson M, Meigs J, Nesto R, Wilson P, Vasan R. Impact of Glucose Intolerance and Insulin Resistance on Cardiac Structure and Function. Circulation 2003, 107: 448-454. PMID: 12551870, DOI: 10.1161/01.cir.0000045671.62860.98.Peer-Reviewed Original ResearchConceptsGlucose tolerance groupInsulin resistanceLV massHOMA-IRGlucose toleranceGlucose intoleranceTolerance groupAbnormal glucose tolerance groupNormal glucose tolerance groupFramingham Study subjectsAbnormal glucose toleranceGlucose tolerance categoriesLeft ventricular hypertrophyBody mass indexLarge community-based sampleLV wall thicknessCommunity-based sampleHeart failureVentricular hypertrophyLA sizeMass indexReferral biasMyocardial infarctionTolerance statusStudy subjects