2014
Body Mass Index and Acute and Long-Term Outcomes After Acute Myocardial Infarction (from the Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction Trial)
Herrmann J, Gersh B, Goldfinger J, Witzenbichler B, Guagliumi G, Dudek D, Kornowski R, Brener S, Parise H, Fahy M, McAndrew T, Stone G, Mehran R. Body Mass Index and Acute and Long-Term Outcomes After Acute Myocardial Infarction (from the Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction Trial). The American Journal Of Cardiology 2014, 114: 9-16. PMID: 24846807, DOI: 10.1016/j.amjcard.2014.03.057.Peer-Reviewed Original ResearchConceptsST-segment myocardial infarctionBody mass indexLong-term outcomesHigher body mass indexBMI quartilesMass indexMyocardial infarctionIschemia-driven target vessel revascularizationAcute Myocardial Infarction trialHigher-weight patientsLower cardiac mortalityLowest BMI quartileCardiovascular risk profileMajor bleeding eventsMyocardial Infarction trialTarget vessel revascularizationLong-term mortalityAcute cardiovascular eventsAcute myocardial infarctionLarge multinational cohortBleeding eventsHarmonizing OutcomesHospital mortalityMyocardial reinfarctionNoncardiac mortality
2004
Obesity and the Risk of New-Onset Atrial Fibrillation
Wang T, Parise H, Levy D, D’Agostino R, Wolf P, Vasan R, Benjamin E. Obesity and the Risk of New-Onset Atrial Fibrillation. JAMA 2004, 292: 2471-2477. PMID: 15562125, DOI: 10.1001/jama.292.20.2471.Peer-Reviewed Original ResearchConceptsBody mass indexNew-onset atrial fibrillationEchocardiographic left atrial diameterLeft atrial diameterAtrial fibrillationRisk factorsAtrial diameterBMI categoriesMass indexAF riskCommunity-based observational cohortNormal body mass indexAge-adjusted incidence ratesInterim myocardial infarctionCardiovascular risk factorsVentricular diastolic dysfunctionBaseline atrial fibrillationClinical risk factorsModifiable risk factorsInfluence of obesityDiastolic dysfunctionAtrial dilatationAtrial dimensionClinical confoundersHazard ratio
2003
Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study
Roubenoff R, Parise H, Payette H, Abad L, D'Agostino R, Jacques P, Wilson P, Dinarello C, Harris T. Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study. The American Journal Of Medicine 2003, 115: 429-435. PMID: 14563498, DOI: 10.1016/j.amjmed.2003.05.001.Peer-Reviewed Original ResearchConceptsIGF-1 levelsInsulin-like growth factor-1Growth factor-1Fat-free massFramingham Heart StudyMass indexInterleukin-6TNF-alphaHeart StudyHigh serum interleukin-6 levelsHigher serum IGF-1 levelsBlood mononuclear cell productionOlder community-dwelling menSerum IGF-1 levelsSerum interleukin-6 levelsCommunity-dwelling older personsFat-free mass indexCommunity-dwelling elderly adultsSerum interleukin-6Interleukin-6 levelsCommunity-dwelling menMononuclear cell productionBody mass indexCytokines TNF-alphaFactor 1Impact of Glucose Intolerance and Insulin Resistance on Cardiac Structure and Function
Rutter M, Parise H, Benjamin E, Levy D, Larson M, Meigs J, Nesto R, Wilson P, Vasan R. Impact of Glucose Intolerance and Insulin Resistance on Cardiac Structure and Function. Circulation 2003, 107: 448-454. PMID: 12551870, DOI: 10.1161/01.cir.0000045671.62860.98.Peer-Reviewed Original ResearchConceptsGlucose tolerance groupInsulin resistanceLV massHOMA-IRGlucose toleranceGlucose intoleranceTolerance groupAbnormal glucose tolerance groupNormal glucose tolerance groupFramingham Study subjectsAbnormal glucose toleranceGlucose tolerance categoriesLeft ventricular hypertrophyBody mass indexLarge community-based sampleLV wall thicknessCommunity-based sampleHeart failureVentricular hypertrophyLA sizeMass indexReferral biasMyocardial infarctionTolerance statusStudy subjects
2002
Overweight and Obesity as Determinants of Cardiovascular Risk: The Framingham Experience
Wilson P, D'Agostino R, Sullivan L, Parise H, Kannel W. Overweight and Obesity as Determinants of Cardiovascular Risk: The Framingham Experience. JAMA Internal Medicine 2002, 162: 1867-1872. PMID: 12196085, DOI: 10.1001/archinte.162.16.1867.Peer-Reviewed Original ResearchConceptsAge-adjusted relative riskBody mass indexCoronary heart diseasePopulation attributable riskRelative riskCardiovascular diseaseCardiovascular sequelaeAngina pectorisExcess weightAttributable riskHeart diseaseOverweight statusRisk factorsCardiovascular disease risk factorsHighest population-attributable riskNew cardiovascular diseaseDisease risk factorsFramingham Heart Study participantsNormal-weight personsDisease end pointsNew hypertensionCardiovascular riskDiabetes mellitusPrimary outcomeMass index