2014
Body Mass Index and Acute and Long-Term Outcomes After Acute Myocardial Infarction (from the Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction Trial)
Herrmann J, Gersh B, Goldfinger J, Witzenbichler B, Guagliumi G, Dudek D, Kornowski R, Brener S, Parise H, Fahy M, McAndrew T, Stone G, Mehran R. Body Mass Index and Acute and Long-Term Outcomes After Acute Myocardial Infarction (from the Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction Trial). The American Journal Of Cardiology 2014, 114: 9-16. PMID: 24846807, DOI: 10.1016/j.amjcard.2014.03.057.Peer-Reviewed Original ResearchConceptsST-segment myocardial infarctionBody mass indexLong-term outcomesHigher body mass indexBMI quartilesMass indexMyocardial infarctionIschemia-driven target vessel revascularizationAcute Myocardial Infarction trialHigher-weight patientsLower cardiac mortalityLowest BMI quartileCardiovascular risk profileMajor bleeding eventsMyocardial Infarction trialTarget vessel revascularizationLong-term mortalityAcute cardiovascular eventsAcute myocardial infarctionLarge multinational cohortBleeding eventsHarmonizing OutcomesHospital mortalityMyocardial reinfarctionNoncardiac mortality
2011
Impact of Diabetes Mellitus on the Safety and Effectiveness of Bivalirudin in Patients With Acute Myocardial Infarction Undergoing Primary Angioplasty Analysis From the HORIZONS-AMI (Harmonizing Outcomes with RevasculariZatiON and Stents in Acute Myocardial Infarction) Trial
Witzenbichler B, Mehran R, Guagliumi G, Dudek D, Huber K, Kornowski R, Stuckey T, Fahy M, Parise H, Stone G. Impact of Diabetes Mellitus on the Safety and Effectiveness of Bivalirudin in Patients With Acute Myocardial Infarction Undergoing Primary Angioplasty Analysis From the HORIZONS-AMI (Harmonizing Outcomes with RevasculariZatiON and Stents in Acute Myocardial Infarction) Trial. JACC Cardiovascular Interventions 2011, 4: 760-768. PMID: 21777884, DOI: 10.1016/j.jcin.2011.04.008.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryAntithrombinsCoronary AngiographyDiabetes MellitusDose-Response Relationship, DrugDouble-Blind MethodElectrocardiographyFemaleFollow-Up StudiesHirudinsHumansHypoglycemic AgentsMaleMiddle AgedMyocardial InfarctionPeptide FragmentsProspective StudiesRecombinant ProteinsStentsSurvival RateTime FactorsTreatment OutcomeConceptsGlycoprotein IIb/IIIa inhibitorsST-segment elevation myocardial infarctionPrimary percutaneous coronary interventionHORIZONS-AMI trialDiabetes mellitusDiabetic patientsMyocardial infarctionPrimary PCIMajor adverse cardiac eventsIIb/IIIa inhibitorsEffectiveness of bivalirudinEfficacy of bivalirudinAdverse cardiac eventsAcute coronary syndromeElevation myocardial infarctionPercutaneous coronary interventionAcute myocardial infarctionMajor bleedingCardiac mortalityCoronary syndromeAnticoagulant therapyCardiac eventsCoronary interventionCardiac deathUnfractionated heparinHeparin plus a glycoprotein IIb/IIIa inhibitor versus bivalirudin monotherapy and paclitaxel-eluting stents versus bare-metal stents in acute myocardial infarction (HORIZONS-AMI): final 3-year results from a multicentre, randomised controlled trial
Stone G, Witzenbichler B, Guagliumi G, Peruga J, Brodie B, Dudek D, Kornowski R, Hartmann F, Gersh B, Pocock S, Dangas G, Wong S, Fahy M, Parise H, Mehran R, Investigators O. Heparin plus a glycoprotein IIb/IIIa inhibitor versus bivalirudin monotherapy and paclitaxel-eluting stents versus bare-metal stents in acute myocardial infarction (HORIZONS-AMI): final 3-year results from a multicentre, randomised controlled trial. The Lancet 2011, 377: 2193-2204. PMID: 21665265, DOI: 10.1016/s0140-6736(11)60764-2.Peer-Reviewed Original ResearchMeSH KeywordsAngioplasty, BalloonCombined Modality TherapyConfidence IntervalsDose-Response Relationship, DrugDrug Administration ScheduleDrug Therapy, CombinationDrug-Eluting StentsElectrocardiographyFemaleFollow-Up StudiesHeparinHirudinsHumansKaplan-Meier EstimateMaleMyocardial InfarctionPaclitaxelPeptide FragmentsPlatelet Glycoprotein GPIIb-IIIa ComplexProspective StudiesRecombinant ProteinsStentsSurvival AnalysisTime FactorsTreatment OutcomeConceptsST-segment elevation myocardial infarctionGlycoprotein IIb/IIIa inhibitorsPrimary percutaneous coronary interventionIIb/IIIa inhibitorsPercutaneous coronary interventionPaclitaxel-eluting stentsBare metal stentsBivalirudin monotherapyStent thrombosisCoronary interventionMyocardial infarctionIschaemia-driven target lesion revascularisationIschaemia-driven target vessel revascularisationMajor adverse cardiovascular eventsComposite adverse eventsHORIZONS-AMI trialPaclitaxel-eluting stentingTarget vessel revascularisationAdverse cardiovascular eventsBypass graft surgeryTarget lesion revascularisationElevation myocardial infarctionOnset of symptomsKaplan-Meier estimatesAcute myocardial infarctionIMPACT OF BIVALIRUDIN PROCEDURAL ANTICOAGULATION IN PATIENTS WITH DIABETES MELLITUS AND ACUTE MYOCARDIAL INFARCTION UNDERGOING PRIMARY ANGIOPLASTY: 3-YEAR RESULTS FROM THE HORIZONS AMI TRIAL
Witzenbichler B, Mehran R, Guagliumi G, Desaga M, Kochman J, Nilsen D, Finkelstein A, Mosseri M, Parise H, Cristea E, Stone G. IMPACT OF BIVALIRUDIN PROCEDURAL ANTICOAGULATION IN PATIENTS WITH DIABETES MELLITUS AND ACUTE MYOCARDIAL INFARCTION UNDERGOING PRIMARY ANGIOPLASTY: 3-YEAR RESULTS FROM THE HORIZONS AMI TRIAL. Journal Of The American College Of Cardiology 2011, 57: e1801. DOI: 10.1016/s0735-1097(11)61801-9.Peer-Reviewed Original ResearchIMPACT OF ASPIRIN DOSE ON LONG TERM CLINICAL OUTCOMES AFTER STENTING FOR ACUTE MYOCARDIAL INFARCTION: 3-YEAR FOLLOW-UP DATA FROM THE HORIZONS-AMI TRIAL
Kovacic J, Mehran R, Dangas G, Claessen B, Parise H, Fahy M, Lansky A, Witzenbichler B, Grines C, Guagliumi G, Kornowski R, Wöhrle J, Dudek D, Weisz G, Stone G. IMPACT OF ASPIRIN DOSE ON LONG TERM CLINICAL OUTCOMES AFTER STENTING FOR ACUTE MYOCARDIAL INFARCTION: 3-YEAR FOLLOW-UP DATA FROM THE HORIZONS-AMI TRIAL. Journal Of The American College Of Cardiology 2011, 57: e1633. DOI: 10.1016/s0735-1097(11)61633-1.Peer-Reviewed Original Research
2010
IVUS PREDICTORS OF EARLY STENT THROMBOSIS AFTER PRIMARY PERCUTANEOUS INTERVENTION IN ACUTE MYOCARDIAL INFARCTION: A HORIZONS-AMI SUBSTUDY
Choi S, Witzenbichler B, Maehara A, Mintz G, Lansky A, Guagliumi G, Brodie B, Kellett M, Parise H, Mehran R, Dangas G, Stone G. IVUS PREDICTORS OF EARLY STENT THROMBOSIS AFTER PRIMARY PERCUTANEOUS INTERVENTION IN ACUTE MYOCARDIAL INFARCTION: A HORIZONS-AMI SUBSTUDY. Journal Of The American College Of Cardiology 2010, 55: a182.e1703. DOI: 10.1016/s0735-1097(10)61704-4.Peer-Reviewed Original ResearchTHE IMPACT OF LEFT VENTRICULAR FUNCTION ON MORTALITY IN PATIENTS WITH ST-SEGMENT ELEVATION ACUTE MYOCARDIAL INFARCTION: ANALYSIS OF THE HARMONIZING OUTCOMES WITH REVASCULARIZATION AND STENTS IN ACUTE MYOCARDIAL INFARCTION (HORIZONS-AMI) STUDY
Lansky A, Ng V, Witzenbichler B, Guagliumi G, Peruga J, Goto K, Parise H, Mehran R, Stone G. THE IMPACT OF LEFT VENTRICULAR FUNCTION ON MORTALITY IN PATIENTS WITH ST-SEGMENT ELEVATION ACUTE MYOCARDIAL INFARCTION: ANALYSIS OF THE HARMONIZING OUTCOMES WITH REVASCULARIZATION AND STENTS IN ACUTE MYOCARDIAL INFARCTION (HORIZONS-AMI) STUDY. Journal Of The American College Of Cardiology 2010, 55: a186.e1741. DOI: 10.1016/s0735-1097(10)61742-1.Peer-Reviewed Original ResearchIMPACT OF PACLITAXEL-ELUTING STENTS IN DIABETIC PATIENTS WITH ACUTE MYOCARDIAL INFARCTION UNDERGOING PRIMARY ANGIOPLASTY: ANALYSIS FROM THE HORIZONS AMI TRIAL
Witzenbichler B, Woehrle J, Guagliumi G, Peruga J, Brodie B, Dudek D, Kornowski R, Hartmann F, Parise H, Lansky A, Nikolsky E, Mehran R, Stone G. IMPACT OF PACLITAXEL-ELUTING STENTS IN DIABETIC PATIENTS WITH ACUTE MYOCARDIAL INFARCTION UNDERGOING PRIMARY ANGIOPLASTY: ANALYSIS FROM THE HORIZONS AMI TRIAL. Journal Of The American College Of Cardiology 2010, 55: a182.e1708. DOI: 10.1016/s0735-1097(10)61709-3.Peer-Reviewed Original Research