2011
Mindful attention reduces neural and self-reported cue-induced craving in smokers
Westbrook C, Creswell JD, Tabibnia G, Julson E, Kober H, Tindle HA. Mindful attention reduces neural and self-reported cue-induced craving in smokers. Social Cognitive And Affective Neuroscience 2011, 8: 73-84. PMID: 22114078, PMCID: PMC3541484, DOI: 10.1093/scan/nsr076.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingMindful attentionCue-induced cravingSmoking cuesSmoking imagesPresent-moment experienceTreatment-seeking smokersPsychophysiological interaction analysisMindfulness-based interventionsSubgenual anterior cingulate cortexAnterior cingulate cortexNeural reactivityNeutral imagesBody of researchMoment experienceNeural markersAddictive disordersCingulate cortexFunctional connectivityNeural activityCuesMindfulnessCravingSmoking cessationAttention
2010
Prefrontal–striatal pathway underlies cognitive regulation of craving
Kober H, Mende-Siedlecki P, Kross EF, Weber J, Mischel W, Hart CL, Ochsner KN. Prefrontal–striatal pathway underlies cognitive regulation of craving. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 14811-14816. PMID: 20679212, PMCID: PMC2930456, DOI: 10.1073/pnas.1007779107.Peer-Reviewed Original ResearchConceptsSubstance use disordersUse disordersPrefrontal cortexVentral tegmental areaSubstance-dependent populationsMore effective treatmentsLong-term consumptionDorsolateral prefrontal cortex activityPrefrontal cortex activityCigarette smokersTegmental areaVentrolateral prefrontal cortexVentral striatum activityVentral striatal activitySubgenual cingulateEffective treatmentLateral prefrontal cortexStriatal activityVentral striatumCortex activityFunctional imagingPhysical healthStriatum activityNeural activityCortex