2024
Impact of Pre-Diagnostic Risk Factors on Short- and Long-Term Ovarian Cancer Survival Trajectories: A Longitudinal Observational Study
Kim S, Tworoger S, Rosen B, McLaughlin J, Risch H, Narod S, Kotsopoulos J. Impact of Pre-Diagnostic Risk Factors on Short- and Long-Term Ovarian Cancer Survival Trajectories: A Longitudinal Observational Study. Cancers 2024, 16: 972. PMID: 38473333, PMCID: PMC11154316, DOI: 10.3390/cancers16050972.Peer-Reviewed Original ResearchOvarian cancer-specific mortalityLongitudinal observational studyAll-cause mortalityCancer-specific mortalityPredictor of ovarian cancer survivalRisk factorsPopulation-based longitudinal observational studyRisk of all-cause mortalityProvincial cancer registryObservational studySurvival trajectoriesInvasive epithelial ovarian cancerHistory of breastfeedingOvarian cancer survivalExtended Cox proportional hazards modelsCox proportional hazards modelsPredictor of all-cause mortalityCancer RegistryAssociated with long-term overall survivalProportional hazards modelLifestyle factorsAll-causeCancer survivalDiagnosis of ovarian cancerOverall survival
2003
Reproductive factors and ovarian cancer risk in Jewish BRCA1 and BRCA2 mutation carriers (United States)
Modugno F, Moslehi R, Ness RB, Nelson DB, Belle S, Kant JA, Wheeler JE, Wonderlick A, Fishman D, Karlan B, Risch H, Cramer DW, Dube MP, Narod SA. Reproductive factors and ovarian cancer risk in Jewish BRCA1 and BRCA2 mutation carriers (United States). Cancer Causes & Control 2003, 14: 439-446. PMID: 12946038, DOI: 10.1023/a:1024932427503.Peer-Reviewed Original ResearchConceptsBRCA1 carriersOC useTubal ligationOvarian cancerReproductive factorsInvasive epithelial ovarian cancerFounder mutationOral contraceptive useHistory of breastfeedingEpithelial ovarian cancerOvarian cancer casesOvarian cancer riskBRCA1 founder mutationsBRCA2 mutation carriersAshkenazi founder mutationsCase-only studyNulliparous womenGynecologic surgeryBRCA1/2 carriersRisk factorsBRCA2 mutationsCancer casesLive birthsBRCA1/2 mutationsContraceptive use