1999
Regulation of autoreactive anti-IgG (Rheumatoid Factor) B cells in normal and autoimmune mice
Wang H, Shlomchik M. Regulation of autoreactive anti-IgG (Rheumatoid Factor) B cells in normal and autoimmune mice. Immunologic Research 1999, 19: 259-270. PMID: 10493179, DOI: 10.1007/bf02786493.Peer-Reviewed Original ResearchConceptsB cellsNormal miceAutoimmune miceAutoimmune diseasesMRL/lpr/lpr miceLpr/lpr miceAutoimmune prone animalsRF B cellsChronic autoimmune diseaseSystemic autoimmune diseaseAntigen-specific mannerAutoreactive B cellsParticular underlying diseaseAutoimmune animalsRF autoantibodiesUnderlying diseaseMaternal IgGLpr miceYoung miceTransgenic miceMiceDiseaseAutoantigensRF clonesCells
1997
High affinity rheumatoid factor transgenic B cells are eliminated in normal mice.
Wang H, Shlomchik M. High affinity rheumatoid factor transgenic B cells are eliminated in normal mice. The Journal Of Immunology 1997, 159: 1125-34. PMID: 9233605, DOI: 10.4049/jimmunol.159.3.1125.Peer-Reviewed Original ResearchConceptsRF B cellsRheumatoid factorB cell toleranceB cellsNormal miceCell toleranceTransgenic modelMRL/lpr miceAutoimmune MRL/lpr miceDisease-related specificitySystemic autoimmune diseaseTransgenic B cellsAutoimmune animalsAutoimmune inductionAutoimmune syndromeMultiple autoantibodiesRheumatoid arthritisLpr miceSerum IgGTolerance inductionAutoimmune diseasesCentral toleranceCognate AgNegative miceNormal animals