2007
The road to modularity
Wagner GP, Pavlicev M, Cheverud JM. The road to modularity. Nature Reviews Genetics 2007, 8: 921-931. PMID: 18007649, DOI: 10.1038/nrg2267.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiodiversityDevelopmental BiologyEvolution, MolecularFossilsGene DuplicationGenesGenetic VariationGenetics, PopulationConceptsProtein-protein interaction networkMolecular systems biologyPatterns of evolutionGene duplicationGene regulationEvolutionary biologyNeutral mutationsBiological organizationQuantitative traitsInteraction networksSystems biologyStructure of macromoleculesEnvironmental conditionsBiologyDuplicationTraitsMutationsRegulationSelectionModularityMacromolecules
2001
Modeling Genetic Architecture: A Multilinear Theory of Gene Interaction
Hansen T, Wagner G. Modeling Genetic Architecture: A Multilinear Theory of Gene Interaction. Theoretical Population Biology 2001, 59: 61-86. PMID: 11243929, DOI: 10.1006/tpbi.2000.1508.Peer-Reviewed Original ResearchConceptsGenotype-phenotype mapGene interactionsQuantitative genetic variationEffects of epistasisGenetic canalizationGenetic experimentsGenetic variationGene substitutionGenetic backgroundEpistasisTractable modelComplex functionsCentral importanceLociBiologyCanalizationPhenotypeGenotypesInteractionSum of linear
2000
Population dependent Fourier decomposition of fitness landscapes over recombination spaces: Evolvability of complex characters
Stadler P, Seitz R, Wagner G. Population dependent Fourier decomposition of fitness landscapes over recombination spaces: Evolvability of complex characters. Bulletin Of Mathematical Biology 2000, 62: 399-428. PMID: 10812714, DOI: 10.1006/bulm.1999.0167.Peer-Reviewed Original Research
1999
Is Hsp90 a regulator of evolvability?
Wagner G, Chiu C, Hansen T. Is Hsp90 a regulator of evolvability? Journal Of Experimental Zoology 1999, 285: 116-118. PMID: 10440722, DOI: 10.1002/(sici)1097-010x(19990815)285:2<116::aid-jez3>3.0.co;2-p.Commentaries, Editorials and LettersMeSH KeywordsAnimalsBiological EvolutionGene Expression RegulationGenetic VariationHSP90 Heat-Shock ProteinsModels, GeneticMutationPhenotype
1996
Apparent Stabilizing Selection and the Maintenance of Neutral Genetic Variation
Wagner G. Apparent Stabilizing Selection and the Maintenance of Neutral Genetic Variation. Genetics 1996, 143: 617-619. PMID: 8722811, PMCID: PMC1207295, DOI: 10.1093/genetics/143.1.617.Peer-Reviewed Original Research