2001
The Topology of the Possible: Formal Spaces Underlying Patterns of Evolutionary Change
STADLER B, STADLER P, WAGNER G, FONTANA W. The Topology of the Possible: Formal Spaces Underlying Patterns of Evolutionary Change. Journal Of Theoretical Biology 2001, 213: 241-274. PMID: 11894994, DOI: 10.1006/jtbi.2001.2423.Peer-Reviewed Original ResearchConceptsGenotype-phenotype mapNeo-Darwinian modelGenotype-phenotype modelsPhenotypic innovationPhenotypic evolutionGenetic accessibilityEvolutionary trajectoriesEvolutionary changeNatural selectionPhenotypic charactersPhenotype spaceGenotype spaceRNA sequencesSecondary structureFitness landscapePossible phenotypesFitness considerationsRNA modelCharacter autonomyPhenotypeRecent computational workFoldingEvolutionRegionSequence
2000
Is the Genotype-Phenotype Map Modular?: A Statistical Approach Using Mouse Quantitative Trait Loci Data
Mezey J, Cheverud J, Wagner G. Is the Genotype-Phenotype Map Modular?: A Statistical Approach Using Mouse Quantitative Trait Loci Data. Genetics 2000, 156: 305-311. PMID: 10978294, PMCID: PMC1461239, DOI: 10.1093/genetics/156.1.305.Peer-Reviewed Original Research