2012
Coming to Grips with Evolvability
Pavlicev M, Wagner G. Coming to Grips with Evolvability. Evolution: Education And Outreach 2012, 5: 231-244. DOI: 10.1007/s12052-012-0430-1.Peer-Reviewed Original ResearchGenotype-phenotype mapOrganismal developmentMost genesCryptic mutationsPhenotypic traitsComplex organismsPhenotypic charactersMost traitsRandom mutationsReal organismsGenetic effectsEvolvabilityGenetic backgroundOrganismsGenesMutationsTraitsNew environmentRandom changesPhenotypeFitnessEvolutionSelectionConventional computer languages
2009
Measuring Evolutionary Constraints Through the Dimensionality of the Phenotype: Adjusted Bootstrap Method to Estimate Rank of Phenotypic Covariance Matrices
Pavlicev M, Wagner G, Cheverud J. Measuring Evolutionary Constraints Through the Dimensionality of the Phenotype: Adjusted Bootstrap Method to Estimate Rank of Phenotypic Covariance Matrices. Evolutionary Biology 2009, 36: 339-353. DOI: 10.1007/s11692-009-9066-7.Peer-Reviewed Original ResearchEvolutionary constraintsCovariance matrixPhenotypic covariance matrixGenetic covariance matrixPhenotypic evolutionBootstrap methodPhenotypic variationGenetic variationPhenotype spaceLack of variationSelection responseFull rankMatrix rankRank estimatesNumber of variablesPhenotypeVariational dimensionsDimensionalityPhenotypicTraitsConstraintsMatrixVariationRankSample size
2006
EVIDENCE FOR THE REVERSIBILITY OF DIGIT LOSS: A PHYLOGENETIC STUDY OF LIMB EVOLUTION IN BACHIA (GYMNOPHTHALMIDAE: SQUAMATA)
Kohlsdorf T, Wagner GP. EVIDENCE FOR THE REVERSIBILITY OF DIGIT LOSS: A PHYLOGENETIC STUDY OF LIMB EVOLUTION IN BACHIA (GYMNOPHTHALMIDAE: SQUAMATA). Evolution 2006, 60: 1896-1912. PMID: 17089974, DOI: 10.1111/j.0014-3820.2006.tb00533.x.Peer-Reviewed Original ResearchConceptsDigit lossSouth American genusMolecular phylogenyLimb evolutionComplex traitsPhylogenetic studiesEvolutionary changeBachiaAmerican generaGenetic informationDigit numberReevolutionMost membersSpecific phenotypesTraitsStrong evidencePhylogenyVisible effectTaxaGenusGenesMorphological structurePhenotypeEvolutionLimited numberEVIDENCE FOR THE REVERSIBILITY OF DIGIT LOSS: A PHYLOGENETIC STUDY OF LIMB EVOLUTION IN BACHIA (GYMNOPHTHALMIDAE: SQUAMATA)
Kohlsdorf T, Wagner G. EVIDENCE FOR THE REVERSIBILITY OF DIGIT LOSS: A PHYLOGENETIC STUDY OF LIMB EVOLUTION IN BACHIA (GYMNOPHTHALMIDAE: SQUAMATA). Evolution 2006, 60: 1896-1912. DOI: 10.1554/06-056.1.Peer-Reviewed Original ResearchDigit lossSouth American genusMolecular phylogenyLimb evolutionComplex traitsPhylogenetic studiesEvolutionary changeBachiaAmerican generaGenetic informationDigit numberReevolutionMost membersSpecific phenotypesTraitsStrong evidencePhylogenyVisible effectTaxaGenusGenesMorphological structurePhenotypeEvolutionLimited number
2001
The Topology of the Possible: Formal Spaces Underlying Patterns of Evolutionary Change
STADLER B, STADLER P, WAGNER G, FONTANA W. The Topology of the Possible: Formal Spaces Underlying Patterns of Evolutionary Change. Journal Of Theoretical Biology 2001, 213: 241-274. PMID: 11894994, DOI: 10.1006/jtbi.2001.2423.Peer-Reviewed Original ResearchConceptsGenotype-phenotype mapNeo-Darwinian modelGenotype-phenotype modelsPhenotypic innovationPhenotypic evolutionGenetic accessibilityEvolutionary trajectoriesEvolutionary changeNatural selectionPhenotypic charactersPhenotype spaceGenotype spaceRNA sequencesSecondary structureFitness landscapePossible phenotypesFitness considerationsRNA modelCharacter autonomyPhenotypeRecent computational workFoldingEvolutionRegionSequenceFunction and the Evolution of Phenotypic Stability: Connecting Pattern to Process1
Schwenk K, Wagner G. Function and the Evolution of Phenotypic Stability: Connecting Pattern to Process1. Integrative And Comparative Biology 2001, 41: 552-563. DOI: 10.1093/icb/41.3.552.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPhenotypic stabilityPhylogenetic character analysisCurrent environmental conditionsSelection differsEnvironmental selectionEnvironmental conditionsInternal selectionExternal selectionSystem-level functionalityCharacter analysisCertain charactersOrganismsSelectionPhenotypeCascadeFunctional integrationCharacterFunctionPatternsResponseWide rangeModeling Genetic Architecture: A Multilinear Theory of Gene Interaction
Hansen T, Wagner G. Modeling Genetic Architecture: A Multilinear Theory of Gene Interaction. Theoretical Population Biology 2001, 59: 61-86. PMID: 11243929, DOI: 10.1006/tpbi.2000.1508.Peer-Reviewed Original ResearchConceptsGenotype-phenotype mapGene interactionsQuantitative genetic variationEffects of epistasisGenetic canalizationGenetic experimentsGenetic variationGene substitutionGenetic backgroundEpistasisTractable modelComplex functionsCentral importanceLociBiologyCanalizationPhenotypeGenotypesInteractionSum of linear
2000
Is the Genotype-Phenotype Map Modular?: A Statistical Approach Using Mouse Quantitative Trait Loci Data
Mezey J, Cheverud J, Wagner G. Is the Genotype-Phenotype Map Modular?: A Statistical Approach Using Mouse Quantitative Trait Loci Data. Genetics 2000, 156: 305-311. PMID: 10978294, PMCID: PMC1461239, DOI: 10.1093/genetics/156.1.305.Peer-Reviewed Original ResearchEvolutionarily Stable Configurations: Functional Integration and the Evolution of Phenotypic Stability
Wagner G, Schwenk K. Evolutionarily Stable Configurations: Functional Integration and the Evolution of Phenotypic Stability. Evolutionary Biology 2000, 155-217. DOI: 10.1007/978-1-4615-4185-1_4.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements