Drug development against the hippo pathway in mesothelioma
Woodard GA, Yang YL, You L, Jablons DM. Drug development against the hippo pathway in mesothelioma. Translational Lung Cancer Research 2017, 6: 335-342. PMID: 28713678, PMCID: PMC5504108, DOI: 10.21037/tlcr.2017.06.02.Peer-Reviewed Original ResearchYAP/TEADCell pathwaysCell contact inhibitionStem cell populationCancer stem cell populationStem cell pathwaysTumor suppressor geneDownstream YAPHippo pathwaySuppressor geneContact inhibitionYAP inhibitorConventional cytotoxic drugsCell populationsMalignant pleural mesotheliomaPathwayDrug developmentTumor resistanceUltimate targetTEADGenesOncogeneYAPEffective chemotherapy drugsChemotherapy drugs