Outcomes of treatment with paclitaxel-coated devices for peripheral arterial disease
Kim TI, Kiwan G, Mohamedali A, Zhang Y, Mena-Hurtado C, Mojibian H, Guzman RJ, Ochoa Chaar CI. Outcomes of treatment with paclitaxel-coated devices for peripheral arterial disease. Journal Of Vascular Surgery 2020, 73: 911-917. PMID: 33038480, DOI: 10.1016/j.jvs.2020.08.146.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAmputation, SurgicalCardiovascular AgentsCoated Materials, BiocompatibleDrug-Eluting StentsEndovascular ProceduresFemaleHumansLimb SalvageMaleMiddle AgedPaclitaxelPeripheral Arterial DiseaseProsthesis DesignRetreatmentRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVascular PatencyConceptsPaclitaxel-coated devicesPeripheral artery diseaseCause of mortalityPCD useRisk of mortalityCumulative doseFemoropopliteal peripheral artery diseaseKaplan-Meier survival curvesLong-term mortalityPeripheral arterial diseaseCox regression analysisDrug-coated balloonsOutcome of treatmentDrug-eluting stentsMajor amputationPrimary patencyReintervention rateArtery diseaseArterial diseaseRandomized trialsOpen surgeryPresent studySingle institutionEndovascular interventionPatientsDistinct subsets of T cells and macrophages impact venous remodeling during arteriovenous fistula maturation
Matsubara Y, Kiwan G, Fereydooni A, Langford J, Dardik A. Distinct subsets of T cells and macrophages impact venous remodeling during arteriovenous fistula maturation. JVS Vascular Science 2020, 1: 207-218. PMID: 33748787, PMCID: PMC7971420, DOI: 10.1016/j.jvssci.2020.07.005.Peer-Reviewed Original ResearchArteriovenous fistulaT cellsVascular remodelingAVF maturationFistula maturationVascular accessEnd-stage renal failureImmunosuppressive drug developmentInflammatory cell subsetsPatent vascular accessArterial blood pressureArteriovenous fistula maturationPreferred vascular accessRegulation of inflammationPrimary patencyTotal immunosuppressionAdaptive vascular remodelingRenal transplantationRenal failureBlood pressureCell subsetsVenous remodelingLonger patencyM2 macrophagesNeointimal hyperplasia