Children of Depressed Parents: Increased Psychopathology and Early Onset of Major Depression
Weissman M, Gammon G, John K, Merikangas K, Warner V, Prusoff B, Sholomskas D. Children of Depressed Parents: Increased Psychopathology and Early Onset of Major Depression. JAMA Psychiatry 1987, 44: 847-853. PMID: 3662741, DOI: 10.1001/archpsyc.1987.01800220009002.Peer-Reviewed Original ResearchConceptsMajor depressionFemale subjectsProband's parentsYears of agePrepubertal depressionPrognostic significanceMean ageOverall prevalenceLower riskClinical strategiesPsychiatric diagnosisPsychiatric treatmentSymptom profilesDepressed probandsNormal probandsDepressed parentsPoor social functioningSubstance abuseEarly onsetDepressed childrenSubject diagnosisDiagnosisDepressionChild psychiatristsSocial functioning