1987
Children of Depressed Parents: Increased Psychopathology and Early Onset of Major Depression
Weissman M, Gammon G, John K, Merikangas K, Warner V, Prusoff B, Sholomskas D. Children of Depressed Parents: Increased Psychopathology and Early Onset of Major Depression. JAMA Psychiatry 1987, 44: 847-853. PMID: 3662741, DOI: 10.1001/archpsyc.1987.01800220009002.Peer-Reviewed Original ResearchConceptsMajor depressionFemale subjectsProband's parentsYears of agePrepubertal depressionPrognostic significanceMean ageOverall prevalenceLower riskClinical strategiesPsychiatric diagnosisPsychiatric treatmentSymptom profilesDepressed probandsNormal probandsDepressed parentsPoor social functioningSubstance abuseEarly onsetDepressed childrenSubject diagnosisDiagnosisDepressionChild psychiatristsSocial functioning
1984
Psychopathology in the Children (Ages 6–18) of Depressed and Normal Parents
WEISSMAN M, PRUSOFF B, GAMMON G, MERIKANGAS K, LECKMAN J, KIDD K. Psychopathology in the Children (Ages 6–18) of Depressed and Normal Parents. Journal Of The American Academy Of Child & Adolescent Psychiatry 1984, 23: 78-84. PMID: 6693680, DOI: 10.1097/00004583-198401000-00011.Peer-Reviewed Original ResearchConceptsDSM-III diagnosesFirst-degree relativesMajor depressionPsychiatric disordersProbands' first-degree relativesChildren of probandsCommon psychiatric disordersDirect interview studyFamily history studyClinical statusPsychiatric illnessNormal controlsDepressed probandsPsychological symptomsSuicidal behaviorEarly onsetDiagnosisDepressionSignificant predictorsProbandsAttention deficitsChildrenRiskEmotional problemsNormal parents