Interobserver Reproducibility of the Myoton and Durometer Devices to Measure Skin Stiffness and Hardness in Chronic Cutaneous Graft-Versus-Host Disease Patients
Chen F, Wang L, Vain A, Ssempijja Y, Dellalana L, Zhang K, Hood A, Chen H, Jagasia M, Tkaczyk E. Interobserver Reproducibility of the Myoton and Durometer Devices to Measure Skin Stiffness and Hardness in Chronic Cutaneous Graft-Versus-Host Disease Patients. Blood 2019, 134: 4515. DOI: 10.1182/blood-2019-129125.Peer-Reviewed Original ResearchIntraclass correlation coefficientCGVHD patientsInterobserver intraclass correlation coefficientSkin stiffness measurementsCutaneous cGVHDInterobserver reproducibilityChronic cutaneous graftCutaneous Graft-VersusHealth Chronic GraftSkin stiffnessHost disease patientsProgression of sclerosisStiffness measurementLongitudinal studyProspective longitudinal studyMinimal detectable changeTherapeutic response measuresDetectable changeChronic graftGraft-VersusHost diseaseSclerotic cGvHDSkin sclerosisCutaneous graftDisease patientsDiagnostic Potential of Five Different Biomechanical Parameters to Detect Sclerotic Cutaneous Graft-Versus-Host Disease
Chen F, Wang L, Ssempijja Y, Vain A, Jagasia M, Tkaczyk E. Diagnostic Potential of Five Different Biomechanical Parameters to Detect Sclerotic Cutaneous Graft-Versus-Host Disease. Blood 2019, 134: 2002. DOI: 10.1182/blood-2019-129381.Peer-Reviewed Original ResearchCGVHD patientsBMT controlsCross-sectional studyHost diseaseSkin sclerosisSkin scoreBiomechanical parametersSclerotic patientsCutaneous Graft-VersusPost-BMT patientsMechanical stress relaxation timeHigh diagnostic yieldProspective longitudinal studyChronic graftGraft-VersusGVHD patientsSkin involvementUnaffected skinUnivariate analysisHealthy controlsMultivariate predictive modelClinician assessmentDiagnostic yieldTreatment responseResponse assessment