1998
Activation of Shaker Potassium Channels
Schoppa N, Sigworth F. Activation of Shaker Potassium Channels. The Journal Of General Physiology 1998, 111: 295-311. PMID: 9450945, PMCID: PMC2222768, DOI: 10.1085/jgp.111.2.295.Peer-Reviewed Original ResearchActivation of Shaker Potassium Channels
Schoppa N, Sigworth F. Activation of Shaker Potassium Channels. The Journal Of General Physiology 1998, 111: 313-342. PMID: 9450946, PMCID: PMC2222769, DOI: 10.1085/jgp.111.2.313.Peer-Reviewed Original Research
1993
Fluctuations in ion channel gating currents. Analysis of nonstationary shot noise
Crouzy S, Sigworth F. Fluctuations in ion channel gating currents. Analysis of nonstationary shot noise. Biophysical Journal 1993, 64: 68-76. PMID: 8381683, PMCID: PMC1262303, DOI: 10.1016/s0006-3495(93)81341-9.Peer-Reviewed Original Research
1991
Open channel noise. VI. Analysis of amplitude histograms to determine rapid kinetic parameters
Heinemann S, Sigworth F. Open channel noise. VI. Analysis of amplitude histograms to determine rapid kinetic parameters. Biophysical Journal 1991, 60: 577-587. PMID: 1718467, PMCID: PMC1260101, DOI: 10.1016/s0006-3495(91)82087-2.Peer-Reviewed Original Research
1990
Yet another approach to the dwell-time omission problem of single-channel analysis
Crouzy S, Sigworth F. Yet another approach to the dwell-time omission problem of single-channel analysis. Biophysical Journal 1990, 58: 731-743. PMID: 1698473, PMCID: PMC1281014, DOI: 10.1016/s0006-3495(90)82416-4.Peer-Reviewed Original ResearchOpen channel noise. V. Fluctuating barriers to ion entry in gramicidin A channels
Heinemann S, Sigworth F. Open channel noise. V. Fluctuating barriers to ion entry in gramicidin A channels. Biophysical Journal 1990, 57: 499-514. PMID: 1689592, PMCID: PMC1280744, DOI: 10.1016/s0006-3495(90)82566-2.Peer-Reviewed Original ResearchMeSH KeywordsAlkanesCations, MonovalentElectric ConductivityGlyceridesGramicidinIon ChannelsLipid BilayersMathematicsModels, BiologicalSqualene
1989
Estimation of Na+ dwell time in the gramicidin A channel. Na+ ions as blockers of H+ currents
Heinemann S, Sigworth F. Estimation of Na+ dwell time in the gramicidin A channel. Na+ ions as blockers of H+ currents. Biochimica Et Biophysica Acta 1989, 987: 8-14. PMID: 2480817, DOI: 10.1016/0005-2736(89)90448-3.Peer-Reviewed Original Research
1988
Open channel noise. IV. Estimation of rapid kinetics of formamide block in gramicidin A channels
Heinemann S, Sigworth F. Open channel noise. IV. Estimation of rapid kinetics of formamide block in gramicidin A channels. Biophysical Journal 1988, 54: 757-764. PMID: 2465033, PMCID: PMC1330382, DOI: 10.1016/s0006-3495(88)83013-3.Peer-Reviewed Original ResearchMeSH KeywordsElectric ConductivityFormamidesGramicidinIon ChannelsKineticsMathematicsMembrane PotentialsModels, BiologicalConceptsBiological ion channelsGramicidin A channelsTime resolutionCurrent histogramFast time scaleOpen channel noiseCharacteristic timeNoise measurementsSingle-channel experimentsNoise experimentsDirect measurementTime scalesA channelsSpectral densityBandwidth limitationsCurrentTheoretical approachMeasurementsIon channelsBlocking processChannelsSingle-channel recordingsSingle-channel currentsNoiseDependence
1987
Open channel noise. III. High-resolution recordings show rapid current fluctuations in gramicidin A and four chemical analogues
Sigworth F, Urry D, Prasad K. Open channel noise. III. High-resolution recordings show rapid current fluctuations in gramicidin A and four chemical analogues. Biophysical Journal 1987, 52: 1055-1064. PMID: 2447969, PMCID: PMC1330105, DOI: 10.1016/s0006-3495(87)83299-x.Peer-Reviewed Original ResearchData transformations for improved display and fitting of single-channel dwell time histograms
Sigworth F, Sine S. Data transformations for improved display and fitting of single-channel dwell time histograms. Biophysical Journal 1987, 52: 1047-1054. PMID: 2447968, PMCID: PMC1330104, DOI: 10.1016/s0006-3495(87)83298-8.Peer-Reviewed Original Research
1986
Open channel noise. II. A test for coupling between current fluctuations and conformational transitions in the acetylcholine receptor
Sigworth F. Open channel noise. II. A test for coupling between current fluctuations and conformational transitions in the acetylcholine receptor. Biophysical Journal 1986, 49: 1041-1046. PMID: 2423148, PMCID: PMC1329684, DOI: 10.1016/s0006-3495(86)83732-8.Peer-Reviewed Original Research