2024
Temporal dynamics in psychological assessments: a novel dataset with scales and response times
Su Z, Liu R, Wei Y, Zhang R, Xu X, Wang Y, Zhu Y, Wang L, Liang L, Wang F, Zhang X. Temporal dynamics in psychological assessments: a novel dataset with scales and response times. Scientific Data 2024, 11: 1046. PMID: 39333112, PMCID: PMC11437125, DOI: 10.1038/s41597-024-03888-8.Peer-Reviewed Original ResearchConceptsPsychological assessmentDiagnosis of mental disordersDomain of psychologyResponse time dataEarly diagnosis of mental disordersPrevalence of mental health issuesMental health issuesGAD-7Mental disordersPsychological screeningScale reliabilityMental healthTemporal dynamicsScreening initiativesHealth issuesPublic healthXinxiang Medical UniversityHealthResponse timeScalePsychologyMedical UniversityVisual environment in schools and student depressive symptoms: Insights from a prospective study across multiple cities in eastern China
Zhang X, Tang J, Wang Y, Yang W, Wang X, Zhang R, Yang J, Lu W, Wang F. Visual environment in schools and student depressive symptoms: Insights from a prospective study across multiple cities in eastern China. Environmental Research 2024, 258: 119490. PMID: 38925465, DOI: 10.1016/j.envres.2024.119490.Peer-Reviewed Original ResearchConceptsStudents' depressive symptomsDepressive symptomsHigh-intensity exercise sessionCombination of physical activityCohort studyHealth Cohort StudyOccurrence of depressive symptomsExercise sessionsPhysical activityFollow-up cohortOne-year follow-upFollow-upOne-year outcomesImpairment groupPhysical examination indicatorsSchool-related factorsModify behaviorPositive effectRR valuesData collectionConsecutive follow-upsPersonal factorsVisual impairmentProspective studyAppropriate attentionDigital Dietary Behaviors in Individuals With Depression: Real-World Behavioral Observation
Zhu Y, Zhang R, Yin S, Sun Y, Womer F, Liu R, Zeng S, Zhang X, Wang F. Digital Dietary Behaviors in Individuals With Depression: Real-World Behavioral Observation. JMIR Public Health And Surveillance 2024, 10: e47428. PMID: 38648087, PMCID: PMC11074900, DOI: 10.2196/47428.Peer-Reviewed Original ResearchConceptsModerate-severe depressionDietary behaviorsMultivariate logistic regression analysisDepression severityMild depressionIrregular eating patternsLogistic regression analysisDetect depressionDinner patternEating breakfastMeal patternsEating patternsDaily lunchSelf-reported dataSupport vector machine analysisBehavior monitoringNaturalistic settingsVector machine analysisFood choicesDepressionProfile of changesBehavioral dataPrediction of the efficacy of group cognitive behavioral therapy using heart rate variability based smart wearable devices: a randomized controlled study
Lin Z, Zheng J, Wang Y, Su Z, Zhu R, Liu R, Wei Y, Zhang X, Wang F. Prediction of the efficacy of group cognitive behavioral therapy using heart rate variability based smart wearable devices: a randomized controlled study. BMC Psychiatry 2024, 24: 187. PMID: 38448895, PMCID: PMC10916138, DOI: 10.1186/s12888-024-05638-x.Peer-Reviewed Original ResearchConceptsGroup cognitive behavioral therapyWait-list controlCognitive behavioral therapyBehavioral therapyEfficacy of group cognitive behavioral therapyGroup cognitive behavioural therapy groupDisabling mental health problemPredictors of treatment responseAssociated with greater improvementTreatment outcomesAssociated with depressionHigher heart rate variabilityMental health problemsHeart rate variabilityAnxious symptomsAnxiety symptomsParticipants' symptomsCollege studentsHRV levelsAnxietyTrial registrationThe trialSignificant public health concernDepressionGreater improvementHeart rate variability parametersDysregulated cerebral blood flow, rather than gray matter Volume, exhibits stronger correlations with blood inflammatory and lipid markers in depression
Kang L, Wang W, Nie Z, Gong Q, Yao L, Xiang D, Zhang N, Tu N, Feng H, Zong X, Bai H, Wang G, Wang F, Bu L, Liu Z. Dysregulated cerebral blood flow, rather than gray matter Volume, exhibits stronger correlations with blood inflammatory and lipid markers in depression. NeuroImage Clinical 2024, 41: 103581. PMID: 38430800, PMCID: PMC10944186, DOI: 10.1016/j.nicl.2024.103581.Peer-Reviewed Original ResearchConceptsGray matter volumeCerebral blood flowMatter volumeArterial spin labelingRight middle temporal gyrusPredictors of MDDMiddle temporal gyrusImmune markersBrain functional changesProportion of MDDExploratory correlation analysisTumor necrosis factor-alphaBlood flowMDD patientsDepressive disorderAngular gyrusTemporal gyrusNecrosis factor-alphaMDDBrain regionsCerebral blood flow changesBlood lipid levelsInferior temporalCase-control comparisonCD4 countState- and trait-related dysfunctions in bipolar disorder across different mood states: a graph theory study
Chen Y, Zhao P, Pan C, Chang M, Zhang X, Duan J, Wei Y, Tang Y, Wang F. State- and trait-related dysfunctions in bipolar disorder across different mood states: a graph theory study. Journal Of Psychiatry And Neuroscience 2024, 49: e11-e22. PMID: 38238036, PMCID: PMC10803102, DOI: 10.1503/jpn.230069.Peer-Reviewed Original ResearchConceptsDepressed BDBipolar disorderEuthymic BDMood statesManic BDDiffusion-tensor imagingHealthy controlsGenetic riskWhite matter networksGlobal efficiencyFrontolimbic circuitsCross-sectional natureStructural topological propertiesGraph theory approachSecondary analysisMedication effectsLocal network changesMoodLocal efficiencyClinical variablesEpisode countsNetwork changesDisordersStructural networkHigh-risk individualsIntegrative omics analysis reveals epigenomic and transcriptomic signatures underlying brain structural deficits in major depressive disorder
Zheng J, Womer F, Tang L, Guo H, Zhang X, Tang Y, Wang F. Integrative omics analysis reveals epigenomic and transcriptomic signatures underlying brain structural deficits in major depressive disorder. Translational Psychiatry 2024, 14: 17. PMID: 38195555, PMCID: PMC10776753, DOI: 10.1038/s41398-023-02724-8.Peer-Reviewed Original ResearchConceptsGray matter volumeBrain structural deficitsFrontal cortexGMV changesStructural deficitsDecreased GMVGray matter volume abnormalitiesInferior frontal cortexAnterior cingulate cortexAllen Human Brain AtlasDifferentially methylated CpG positionsGray matter abnormalitiesHuman Brain AtlasRegionally specific correlationsDepressive disorderCingulate cortexMatter volumeMorphological deficitsMDDBetween-group differencesCortex regionsCortexSynaptic transmission processesDeficitsHealthy controls
2023
Prediction of anxious depression using multimodal neuroimaging and machine learning
Zhou E, Wang W, Ma S, Xie X, Kang L, Xu S, Deng Z, Gong Q, Nie Z, Yao L, Bu L, Wang F, Liu Z. Prediction of anxious depression using multimodal neuroimaging and machine learning. NeuroImage 2023, 285: 120499. PMID: 38097055, DOI: 10.1016/j.neuroimage.2023.120499.Peer-Reviewed Original Research
2009
Functional and Structural Connectivity Between the Perigenual Anterior Cingulate and Amygdala in Bipolar Disorder
Wang F, Kalmar JH, He Y, Jackowski M, Chepenik LG, Edmiston E, Tie K, Gong G, Shah MP, Jones M, Uderman J, Constable RT, Blumberg HP. Functional and Structural Connectivity Between the Perigenual Anterior Cingulate and Amygdala in Bipolar Disorder. Biological Psychiatry 2009, 66: 516-521. PMID: 19427632, PMCID: PMC2830492, DOI: 10.1016/j.biopsych.2009.03.023.Peer-Reviewed Original ResearchConceptsPerigenual anterior cingulate cortexHealthy comparison subjectsBipolar disorderFunctional magnetic resonance imagingDiffusion tensor imagingFunctional connectivityWhite matterFractional anisotropyHC groupPerigenual anterior cingulateAnterior cingulate cortexMagnetic resonance imagingGray matter structuresRegional fractional anisotropyWhite matter connectivityEmotional processingFunctional connectivity measuresSignificant positive associationBD groupComparison subjectsAnterior cingulateCingulate cortexResonance imagingSignificant associationBrain regionsNeuregulin 1 genetic variation and anterior cingulum integrity in patients with schizophrenia and healthy controls.
Wang F, Jiang T, Sun Z, Teng SL, Luo X, Zhu Z, Zang Y, Zhang H, Yue W, Qu M, Lu T, Hong N, Huang H, Blumberg HP, Zhang D. Neuregulin 1 genetic variation and anterior cingulum integrity in patients with schizophrenia and healthy controls. Journal Of Psychiatry And Neuroscience 2009, 34: 181-6. PMID: 19448847, PMCID: PMC2674970.Peer-Reviewed Original ResearchConceptsAnterior cingulumFractional anisotropyHealthy controlsBrain regionsDiagnosis of schizophreniaDiffusion tensorWhite matter connectivityHealthy menWhite matter structuresT carriersMyelin integrityTT subgroupPatientsProminent involvementT alleleReciprocal connectionsAnterior componentC alleleCingulum bundleSchizophrenia groupGenetic susceptibilityCingulum fractional anisotropyNeuregulin1SchizophreniaSmall sample size
2008
Influence of Vascular Endothelial Growth Factor Variation on Human Hippocampus Morphology
Blumberg HP, Wang F, Chepenik LG, Kalmar JH, Edmiston E, Duman RS, Gelernter J. Influence of Vascular Endothelial Growth Factor Variation on Human Hippocampus Morphology. Biological Psychiatry 2008, 64: 901-903. PMID: 18707678, PMCID: PMC2649728, DOI: 10.1016/j.biopsych.2008.07.003.Peer-Reviewed Original ResearchAbnormal anterior cingulum integrity in bipolar disorder determined through diffusion tensor imaging
Wang F, Jackowski M, Kalmar JH, Chepenik LG, Tie K, Qiu M, Gong G, Pittman BP, Jones MM, Shah MP, Spencer L, Papademetris X, Constable RT, Blumberg HP. Abnormal anterior cingulum integrity in bipolar disorder determined through diffusion tensor imaging. The British Journal Of Psychiatry 2008, 193: 126-129. PMID: 18669996, PMCID: PMC2732002, DOI: 10.1192/bjp.bp.107.048793.Peer-Reviewed Original ResearchConceptsBipolar disorderWhite matter connectionsFractional anisotropyAnterior cingulumPosterior cingulumAbnormal white matter integrityWhite matter abnormalitiesBipolar disorder groupAnterior cingulate cortexDiffusion tensorWhite matter integrityHealthy groupCingulate cortexNeural systemsHealthy participantsDisorder groupDisordersAbnormalitiesCingulumConvergent evidenceGroupParticipantsEmotional regulationAbnormal Corpus Callosum Integrity in Bipolar Disorder: A Diffusion Tensor Imaging Study
Wang F, Kalmar JH, Edmiston E, Chepenik LG, Bhagwagar Z, Spencer L, Pittman B, Jackowski M, Papademetris X, Constable RT, Blumberg HP. Abnormal Corpus Callosum Integrity in Bipolar Disorder: A Diffusion Tensor Imaging Study. Biological Psychiatry 2008, 64: 730-733. PMID: 18620337, PMCID: PMC2586998, DOI: 10.1016/j.biopsych.2008.06.001.Peer-Reviewed Original Research