2017
Vascular inflammation and metabolic activity in hematopoietic organs and liver in familial combined hyperlipidemia and heterozygous familial hypercholesterolemia
Toutouzas K, Skoumas J, Koutagiar I, Benetos G, Pianou N, Georgakopoulos A, Galanakos S, Antonopoulos A, Drakopoulou M, Oikonomou EK, Kafouris P, Athanasiadis E, Metaxas M, Spyrou G, Pallantza Z, Galiatsatos N, Aggeli C, Antoniades C, Keramida G, Peters AM, Anagnostopoulos CD, Tousoulis D. Vascular inflammation and metabolic activity in hematopoietic organs and liver in familial combined hyperlipidemia and heterozygous familial hypercholesterolemia. Journal Of Clinical Lipidology 2017, 12: 33-43. PMID: 29174439, DOI: 10.1016/j.jacl.2017.10.019.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiomarkersBone MarrowCase-Control StudiesC-Reactive ProteinFemaleHeterozygoteHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHyperlipidemia, Familial CombinedHyperlipoproteinemia Type IIInflammationLipoproteins, LDLLiverMaleMiddle AgedPositron Emission Tomography Computed TomographySpleenConceptsHeFH patientsFDG uptakeAortic TBRVascular inflammationBone marrowFamilial dyslipidemiaHigher low-density lipoprotein levelsF-fluorodeoxyglucose positron emission tomography/High-sensitivity C-reactive proteinBone marrow FDG uptakeLow-density lipoprotein levelsPositron emission tomography/C-reactive proteinHigh FDG uptakeHeterozygous familial hypercholesterolemiaLow-density lipoproteinHepatic metabolic activityHematopoietic organsHigh liver uptakeDyslipidemic groupAdult patientsCardiovascular riskInflammatory biomarkersSerum lipidsAccelerated atherogenesis
2015
The role of microRNAs in coronary artery disease: From pathophysiology to diagnosis and treatment
Economou EK, Oikonomou E, Siasos G, Papageorgiou N, Tsalamandris S, Mourouzis K, Papaioanou S, Tousoulis D. The role of microRNAs in coronary artery disease: From pathophysiology to diagnosis and treatment. Atherosclerosis 2015, 241: 624-633. PMID: 26117399, DOI: 10.1016/j.atherosclerosis.2015.06.037.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAnimalsApoptosisAtherosclerosisBiomarkersBlood PlateletsCell MovementCoronary Artery DiseaseDisease ProgressionEndothelium, VascularGene Expression RegulationHumansLipoproteins, HDLLipoproteins, LDLMiceMicroRNAsMonocytesMuscle, Smooth, VascularMyocardial InfarctionNeovascularization, PathologicOligonucleotidesReperfusion InjuryStem CellsConceptsCoronary artery diseaseDevelopment of atherosclerosisArtery diseaseCoronary artery disease progressionPathogenesis of atherosclerosisStudy of miRNAsMyocardial infarctionDisease progressionSpecific miRNA expression patternsTherapeutic approachesRole of microRNAsPreventive opportunitiesDiagnostic biomarkersRelated conditionsAtherosclerosisMiRNA expression patternsDiseaseNon-coding RNA moleculesRole of miRNAsIntercellular communicationIntracellular regulatorsExpression patternsMiRNAsPost-transcriptional levelGene expression