2021
Non-steroidal treatment of cardiac sarcoidosis: A systematic review
Gallegos C, Oikonomou EK, Grimshaw A, Gulati M, Young BD, Miller EJ. Non-steroidal treatment of cardiac sarcoidosis: A systematic review. IJC Heart & Vasculature 2021, 34: 100782. PMID: 33997256, PMCID: PMC8105294, DOI: 10.1016/j.ijcha.2021.100782.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsNon-steroidal treatmentSteroid-sparing agentCardiac sarcoidosisSafety profileSystematic reviewCases of CSDisease-modifying antirheumatic agentsManagement of CSActive cardiac sarcoidosisAnti-inflammatory managementAverage corticosteroid doseHigher-line treatmentsMaintenance steroid doseFirst-line treatmentSide effect profileSteroid-sparing therapiesInception of databasesLong-term useCorticosteroid doseSteroid doseBiologic DMARDsImmunosuppressive therapyTreatment initiationEffect profileImmunosuppressive agents
2019
Meta-Analysis of Transthoracic Echocardiography Versus Cardiac Magnetic Resonance for the Assessment of Aortic Regurgitation After Transcatheter Aortic Valve Implantation
Papanastasiou CA, Kokkinidis DG, Jonnalagadda AK, Oikonomou EK, Kampaktsis PN, Garcia MJ, Myerson SG, Karamitsos TD. Meta-Analysis of Transthoracic Echocardiography Versus Cardiac Magnetic Resonance for the Assessment of Aortic Regurgitation After Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2019, 124: 1246-1251. PMID: 31466694, DOI: 10.1016/j.amjcard.2019.07.036.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationCardiac magnetic resonanceSevere aortic regurgitationAortic regurgitationAortic valve implantationValve implantationPost-TAVI aortic regurgitationHierarchical summary receiver operator characteristic curveSeverity of ARLevel of agreementDiagnostic accuracyResidual aortic regurgitationReceiver operator characteristic curveOperator characteristic curveTransthoracic echocardiographyEchocardiographic assessmentMajor complicationsSummary receiver operator characteristic curveMagnetic resonanceAR assessmentElectronic databasesMeta-AnalysisSystematic reviewClinical settingKappa coefficientThe Prognostic Role of Late Gadolinium Enhancement in Aortic Stenosis A Systematic Review and Meta-Analysis
Papanastasiou CA, Kokkinidis DG, Kampaktsis PN, Bikakis I, Cunha DK, Oikonomou EK, Greenwood JP, Garcia MJ, Karamitsos TD. The Prognostic Role of Late Gadolinium Enhancement in Aortic Stenosis A Systematic Review and Meta-Analysis. JACC Cardiovascular Imaging 2019, 13: 385-392. PMID: 31326491, DOI: 10.1016/j.jcmg.2019.03.029.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementAortic stenosisCardiac magnetic resonanceCause mortalityGadolinium enhancementLGE-CMRSystematic reviewA Systematic ReviewStrongest univariate predictorsRandom-effects modelBaseline characteristicsHazard ratioPrognostic roleRisk stratificationAdverse outcomesPrognostic valueUnivariate predictorsPooled analysisMyocardial fibrosisInclusion criteriaCardiac diseaseRegional fibrosisPatientsElectronic databasesMeta-Analysis
2018
The predictive value of baseline pulmonary hypertension in early and long term cardiac and all-cause mortality after transcatheter aortic valve implantation for patients with severe aortic valve stenosis: A systematic review and meta-analysis
Kokkinidis DG, Papanastasiou CA, Jonnalagadda AK, Oikonomou EK, Theochari CA, Palaiodimos L, Karvounis HI, Armstrong EJ, Faillace RT, Giannakoulas G. The predictive value of baseline pulmonary hypertension in early and long term cardiac and all-cause mortality after transcatheter aortic valve implantation for patients with severe aortic valve stenosis: A systematic review and meta-analysis. Cardiovascular Revascularization Medicine 2018, 19: 859-867. PMID: 29724516, DOI: 10.1016/j.carrev.2018.03.015.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationElevated pulmonary artery pressurePulmonary artery pressureAortic valve stenosisSevere aortic valve stenosisSurgical aortic valve replacementBaseline pulmonary hypertensionPulmonary hypertensionAortic valve implantationArtery pressureCause mortalityHazard ratioSystematic reviewValve implantationValve stenosisRelative riskAssociation of PHBaseline pulmonary artery pressurePulmonary artery systolic pressureChronic obstructive pulmonary diseaseAortic valve replacementLate cardiac mortalityObstructive pulmonary diseaseRandom-effects modelMeta-regression analysisHeart transplantation versus left ventricular assist devices as destination therapy or bridge to transplantation for 1-year mortality: a systematic review and meta-analysis.
Theochari CA, Michalopoulos G, Oikonomou EK, Giannopoulos S, Doulamis IP, Villela MA, Kokkinidis DG. Heart transplantation versus left ventricular assist devices as destination therapy or bridge to transplantation for 1-year mortality: a systematic review and meta-analysis. Annals Of Cardiothoracic Surgery 2018, 7: 3-11. PMID: 29492379, PMCID: PMC5827119, DOI: 10.21037/acs.2017.09.18.Peer-Reviewed Original ResearchDestination therapyLate mortalityVentricular assist deviceHeart transplantationAssist deviceAvailable studiesSystematic reviewAdvanced heart failure patientsLVAD destination therapyHeart failure patientsCochrane CENTRAL databasesMeta-Analyses (PRISMA) guidelinesPreferred Reporting ItemsRandom-effects modelBTT-LVADCause mortalityFailure patientsMortality benefitAdvanced HFInvasive managementOptimal treatmentDT LVADPooled estimatesHTxReporting Items
2016
The effect of in-hospital acquired thrombocytopenia on the outcome of patients with acute coronary syndromes: A systematic review and meta-analysis
Oikonomou EK, Repanas TI, Papanastasiou C, Kokkinidis DG, Miligkos M, Feher A, Gupta D, Kampaktsis PN. The effect of in-hospital acquired thrombocytopenia on the outcome of patients with acute coronary syndromes: A systematic review and meta-analysis. Thrombosis Research 2016, 147: 64-71. PMID: 27689317, PMCID: PMC5515466, DOI: 10.1016/j.thromres.2016.09.026.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeNew onset thrombocytopeniaACS patientsCoronary syndromePlatelet countHigh riskSystematic reviewLong-term adverse eventsHospital heart failureSecondary cardiovascular endpointsMajor bleeding eventsOutcomes of patientsRecurrent myocardial infarctionAbnormal platelet countDevelopment of thrombocytopeniaShort-term mortalityLong-term outcomesNormal platelet countBleeding eventsHospital thrombocytopeniaLate deathsUnplanned revascularizationHospital stayAdverse eventsCardiovascular endpoints