ATP6v0d2 deficiency increases bone mass, but does not influence ovariectomy-induced bone loss
Kim T, Ha H, Kim N, Park E, Rho J, Kim E, Lorenzo J, Choi Y, Lee S. ATP6v0d2 deficiency increases bone mass, but does not influence ovariectomy-induced bone loss. Biochemical And Biophysical Research Communications 2010, 403: 73-78. PMID: 21040703, PMCID: PMC3026595, DOI: 10.1016/j.bbrc.2010.10.117.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBone and BonesBone DensityCell DifferentiationMiceMice, KnockoutOsteoclastsOsteoporosisVacuolar Proton-Translocating ATPasesConceptsColony forming unit-granulocyte/macrophageBone lossActions of bone-forming osteoblastsOsteoclast maturationOvariectomy (OVX)-induced bone lossOVX-induced bone lossBone homeostasisOVX-induced increaseIncreased bone resorptionBone marrow cellsOsteoclast formation in vitroExcessive bone lossPathological conditionsNormal developmentBone-forming osteoblastsBone-resorbing osteoclastsControl of bone homeostasisMarrow cellsBone massProtect miceBone resorptionFormation in vitroOsteoclast differentiationOsteoclast precursorsAtp6v0d2