Association between fine particulate matter and eczema: A cross-sectional study of the All of Us Research Program and the Center for Air, Climate, and Energy Solutions.
Chen G, Hwang E, Leonard C, Cohen J. Association between fine particulate matter and eczema: A cross-sectional study of the All of Us Research Program and the Center for Air, Climate, and Energy Solutions. PLOS ONE 2024, 19: e0310498. PMID: 39536018, PMCID: PMC11560005, DOI: 10.1371/journal.pone.0310498.Peer-Reviewed Original ResearchConceptsPM2.5 concentrationsAmbient air pollutionUs Research ProgramAir pollutionCross-sectional studyAnnual PM2.5 concentrationCohort of American adultsPM2.5 exposureParticulate matterPM2.5Odds of eczemaPrevalence of eczemaAssociated with eczemaRisk of eczemaEnvironmental hazardsAtopic comorbiditiesPollutionSmoking statusTargeted interventionsZip codesAmerican adultsLogistic regressionAmerican cohortDemographic factorsOne-way analysis of varianceFacile adipocyte uptake and liver/adipose tissue delivery of conjugated linoleic acid-loaded tocol nanocarriers for a synergistic anti-adipogenesis effect
Hsu C, Liao C, Lin Z, Alalaiwe A, Hwang E, Lin T, Fang J. Facile adipocyte uptake and liver/adipose tissue delivery of conjugated linoleic acid-loaded tocol nanocarriers for a synergistic anti-adipogenesis effect. Journal Of Nanobiotechnology 2024, 22: 50. PMID: 38317220, PMCID: PMC10845550, DOI: 10.1186/s12951-024-02316-8.Peer-Reviewed Original ResearchConceptsAcetyl-CoA carboxylaseFatty acid synthaseAnti-adipogenesis effectConjugated linoleic acidLipogenic enzymes acetyl-CoA carboxylaseEnzyme acetyl-CoA carboxylaseNanostructured lipid carriersIn vitro adipocyte modelsAnti-adipogenic activityAcid synthaseAdipogenesis inhibitionAdipocyte modelInhibit adipogenesisAdipose tissueAdipocytesAdipogenesisAdipocyte hypertrophyIn vivo rat modelLipid-based nanocarriersA-tocopherolReduced body weightObese ratsRat modelTotal cholesterolFat accumulation