2023
Randomized trial comparing standard versus light intensity parent training for anxious youth
Storch E, Guzick A, Ayton D, Palo A, Kook M, Candelari A, Maye C, McNeel M, Trent E, Garcia J, Onyeka O, Rast C, Shimshoni Y, Lebowitz E, Goodman W. Randomized trial comparing standard versus light intensity parent training for anxious youth. Behaviour Research And Therapy 2023, 173: 104451. PMID: 38154287, DOI: 10.1016/j.brat.2023.104451.Peer-Reviewed Original ResearchObsessive-compulsive disorderAnxiety severityAnxious Childhood EmotionsParent-reported anxietyPost-treatment anxietyTreatment conditionsAnxious youthChildhood EmotionsParent trainingFamily accommodationSupportive parentingAnxiety treatmentDiverse sampleAnxietyOne monthSignificant anxietyYouthChange scoresIndependent evaluatorsFunctional impairmentParentsFurther supportSessionsTotal change scoresEmotionsParent Accommodation Contemporaneously Mediates the Association Between Youth Irritability and Youth Anxiety Treatment Outcome
Cabrera V, Buitron V, Patriarca G, Rey Y, Lebowitz E, Silverman W, Pettit J. Parent Accommodation Contemporaneously Mediates the Association Between Youth Irritability and Youth Anxiety Treatment Outcome. Behavior Therapy 2023, 54: 852-862. PMID: 37597962, PMCID: PMC10440415, DOI: 10.1016/j.beth.2023.03.002.Peer-Reviewed Original ResearchConceptsYouth anxiety severityParent accommodationCognitive-behavioral treatmentYouth irritabilityAnxiety treatment outcomesAnxiety severityChild anxietyPrimary anxiety disorder diagnosisAnxiety disorder diagnosisAnxious youthYouth anxietyYouth ages 6Adolescent irritabilityAnxiety outcomesBehavioral treatmentAnxiety protocolAnxietyGreater impairmentDisorder diagnosisAge 6Treatment outcomesFuture researchPosttreatmentIrritabilityResearch documentsThe Role of Family-Level Factors in Childhood Anxiety During the COVID-19 Pandemic
Kitt E, Cohodes E, McCauley S, Hommel G, Nardini C, Zacharek S, Martino A, Anderson T, Spencer H, Odriozola P, Spurrier G, Broussard A, Marin C, Silverman W, Lebowitz E, Gee D. The Role of Family-Level Factors in Childhood Anxiety During the COVID-19 Pandemic. Journal Of Emotion And Psychopathology 2023, 1: 129-151. DOI: 10.55913/joep.v1i1.18.Peer-Reviewed Original ResearchCOVID-19-related fearCOVID-19-related stressFamily-level factorsAmygdala reactivityAnxiety disordersChildren's useEmotion regulation strategiesParent-child dynamicsExpressive suppressionAnxious youthFearful facesChildhood anxietyFMRI taskPediatric anxietyRegulation strategiesOwn functioningCOVID-19 pandemicFamily exposureMultimodal studyFearPervasive disruptionChildren's exposureFamily lifeParental assistanceAnxiety
2018
Negative peer social interactions and oxytocin levels linked to suicidal ideation in anxious youth
Lebowitz ER, Blumberg HP, Silverman WK. Negative peer social interactions and oxytocin levels linked to suicidal ideation in anxious youth. Journal Of Affective Disorders 2018, 245: 806-811. PMID: 30699863, PMCID: PMC6361537, DOI: 10.1016/j.jad.2018.11.070.Peer-Reviewed Original ResearchConceptsNegative peer interactionsPeer social interactionSalivary oxytocin levelsAnxious youthPeer interactionsHigher oxytocin levelsAnxiety disordersOxytocin levelsSocial interactionSuicidal ideationSocial eventsSelf-report measuresPrimary anxiety disorderSemi-structured diagnostic interviewNegative social interactionsPeripheral oxytocin levelsSample of childrenPeer victimization
2017
Monotherapy Insufficient in Severe Anxiety? Predictors and Moderators in the Child/Adolescent Anxiety Multimodal Study
Taylor JH, Lebowitz ER, Jakubovski E, Coughlin CG, Silverman WK, Bloch MH. Monotherapy Insufficient in Severe Anxiety? Predictors and Moderators in the Child/Adolescent Anxiety Multimodal Study. Journal Of Clinical Child & Adolescent Psychology 2017, 47: 266-281. PMID: 28956620, PMCID: PMC6191182, DOI: 10.1080/15374416.2017.1371028.Peer-Reviewed Original ResearchConceptsChild/Adolescent Anxiety Multimodal StudyCognitive behavioral therapyModerators of outcomeSevere anxietyCombination of CBTIndependent evaluator ratingsMultimodal studyParent-rated anxietySeparation anxiety disorderMain effect findingsObsessive-compulsive disorderAnxious youthSocial anxietyChild anxietyBehavioral therapyAnxiety severityPill placeboAnxiety disordersEvaluators' ratingsAnxietyModeratorSocioeconomic statusLow socioeconomic statusYouthEffect findingsOxytocin response to youth–mother interactions in clinically anxious youth is associated with separation anxiety and dyadic behavior
Lebowitz ER, Silverman WK, Martino AM, Zagoory‐Sharon O, Feldman R, Leckman JF. Oxytocin response to youth–mother interactions in clinically anxious youth is associated with separation anxiety and dyadic behavior. Depression And Anxiety 2017, 34: 127-136. PMID: 28052452, PMCID: PMC5503301, DOI: 10.1002/da.22585.Peer-Reviewed Original ResearchConceptsSeparation anxiety disorderAnxious youthAnxiety disordersSeparation anxietySalivary oxytocinAffective touchDSM-5 anxiety disordersYouth anxiety symptomsOT responseParticular anxiety disordersAttachment figuresReliable codersMaternal sensitivityDyadic behaviorsChildren's ratingsMaternal intrusivenessAttachment behaviorAnxiety symptomsAnxiety regulationSocial supportPossible intervention strategiesSignificant distressHigher youthYouthIntervention strategies
2015
Salivary oxytocin in clinically anxious youth: Associations with separation anxiety and family accommodation
Lebowitz ER, Leckman JF, Feldman R, Zagoory-Sharon O, McDonald N, Silverman WK. Salivary oxytocin in clinically anxious youth: Associations with separation anxiety and family accommodation. Psychoneuroendocrinology 2015, 65: 35-43. PMID: 26716876, PMCID: PMC4895196, DOI: 10.1016/j.psyneuen.2015.12.007.Peer-Reviewed Original ResearchConceptsSalivary OT levelsFamily accommodationSeparation anxiety disorderYouth anxietyAnxiety disordersAnxious youthInterpersonal behaviorSeparation anxietyOT levelsDSM-5 anxiety disordersSeparation anxiety symptomsTreatment of anxietyNeuropeptide oxytocinSalivary OTClinical anxietyMaternal ratingsSalivary oxytocinAnxiety symptomsOxytocinergic systemRegulation of anxietyAnxious behaviorOwn behaviorAnxiety assessmentAnxietyParental involvementAnxiety sensitivity moderates behavioral avoidance in anxious youth
Lebowitz ER, Shic F, Campbell D, Basile K, Silverman WK. Anxiety sensitivity moderates behavioral avoidance in anxious youth. Behaviour Research And Therapy 2015, 74: 11-17. PMID: 26348546, PMCID: PMC4895193, DOI: 10.1016/j.brat.2015.08.009.Peer-Reviewed Original ResearchConceptsAnxiety sensitivityFear of spidersSensations of anxietyBehavioral avoidanceSpider stimuliAnxious youthRole of ASAvoidant behaviorAnxiety treatmentOverall avoidanceAnxietyStimuliYouthFearStrongest predictorAvoidancePatient's abilityIndividualsSensationModeratesAbilityImplicationsPredictorsSupportBehavior