2021
Diagnostic safety of a machine learning-based automatic patient selection algorithm for stress-only myocardial perfusion SPECT
Eisenberg E, Miller RJH, Hu LH, Rios R, Betancur J, Azadani P, Han D, Sharir T, Einstein AJ, Bokhari S, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Liang JX, Otaki Y, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Diagnostic safety of a machine learning-based automatic patient selection algorithm for stress-only myocardial perfusion SPECT. Journal Of Nuclear Cardiology 2021, 29: 2295-2307. PMID: 34228341, PMCID: PMC9020793, DOI: 10.1007/s12350-021-02698-4.Peer-Reviewed Original ResearchConceptsObstructive coronary artery diseaseCoronary artery diseaseHigh-risk coronary artery diseaseMyocardial perfusion imagingPatient selection algorithmTriple-vessel coronary artery diseasePrediction of CADML thresholdsStress-first protocolInvasive coronary angiographyReceiver operator characteristic curveOperator characteristic curveMyocardial perfusion SPECTArtery diseaseCoronary angiographyAnterior descendingClinical variablesClinical algorithmReader diagnosisRest imagingPerfusion SPECTPerfusion imagingDiagnostic safetyRadiation doseCharacteristic curve
2020
Prognostically safe stress-only single-photon emission computed tomography myocardial perfusion imaging guided by machine learning: report from REFINE SPECT
Hu LH, Miller RJH, Sharir T, Commandeur F, Rios R, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Liang JX, Eisenberg E, Dey D, Berman DS, Slomka PJ. Prognostically safe stress-only single-photon emission computed tomography myocardial perfusion imaging guided by machine learning: report from REFINE SPECT. European Heart Journal - Cardiovascular Imaging 2020, 22: 705-714. PMID: 32533137, DOI: 10.1093/ehjci/jeaa134.Peer-Reviewed Original ResearchConceptsMajor adverse cardiac eventsPhysician interpretationMACE rateCancellation rateTomography myocardial perfusion imagingAdverse cardiac eventsInternational multicentre registryCause mortality ratesMyocardial perfusion imagingCurrent clinical approachesSingle photon emissionMulticentre registryCardiac eventsClinical dataMortality ratePerfusion imagingClinical approachPatientsML thresholdsRadiation exposureMPI scansPhoton emissionML scoreMLSafety