The regulation of DNA supercoiling across evolution
Duprey A, Groisman EA. The regulation of DNA supercoiling across evolution. Protein Science 2021, 30: 2042-2056. PMID: 34398513, PMCID: PMC8442966, DOI: 10.1002/pro.4171.Peer-Reviewed Original ResearchMeSH KeywordsArchaeaBacteriaDNA ReplicationDNA, ArchaealDNA, BacterialDNA, SuperhelicalEvolution, MolecularConceptsDomains of lifeDNA supercoilingCellular processesAbnormal DNA replicationCertain cellular processesActivity of topoisomerasesChromosome replicationGlobal supercoilingNegative supercoilsDNA replicationBiological questionsSupercoilingEukaryotic topoisomerasesTopoisomerasesSupercoilsSignificant therapeutic potentialOrganismsHelix structureBacteriaPhysicochemical factorsRegulationDouble helix structureReplicationUnique strategyArchaea