Age-dependent pathogenic profiles of enterotoxigenic Escherichia coli diarrhea in Bangladesh
Akhtar M, Begum Y, Rahman S, Afrad M, Parvin N, Akter A, Tauheed, Amin M, Ryan E, Khan A, Chowdhury F, Bhuiyan T, Qadri F. Age-dependent pathogenic profiles of enterotoxigenic Escherichia coli diarrhea in Bangladesh. Frontiers In Public Health 2024, 12: 1484162. DOI: 10.3389/fpubh.2024.1484162.Peer-Reviewed Original ResearchEnterotoxigenic Escherichia coliETEC infectionColonization factorsEnterotoxigenic Escherichia coli strainsEnterotoxigenic Escherichia coli infectionEnterotoxigenic Escherichia coli diarrheaETEC casesClinical manifestationsETEC-associated diarrheaHost-pathogen interactionsAge groupsPrevalence of antimicrobial resistanceDevelopment of targeted vaccinesETEC antigensETEC diarrheaVirulence factorsYears age groupDiarrheal patientsHospital surveillance dataToxin typesAge-specific distributionChildren aged 0Pediatric casesAntimicrobial resistanceCFA/ICholera toxin and O-specific polysaccharide immune responses after oral cholera vaccination with Dukoral in different age groups of Bangladeshi participants
Dash P, Hakim A, Akter A, Banna H, Kaisar M, Aktar A, Jahan S, Ferdous J, Basher S, Kamruzzaman M, Chowdhury F, Akter A, Tauheed I, Weil A, Charles R, Calderwood S, Ryan E, LaRocque R, Harris J, Bhuiyan T, Qadri F. Cholera toxin and O-specific polysaccharide immune responses after oral cholera vaccination with Dukoral in different age groups of Bangladeshi participants. MSphere 2024, 9: e00565-23. PMID: 38391226, PMCID: PMC10964428, DOI: 10.1128/msphere.00565-23.Peer-Reviewed Original ResearchB cell responsesMemory B cell responsesClass-switched antibody responsesOral cholera vaccineAntibody responseImmune responseCholera toxin B subunitCholera vaccineToxin B subunitAge groupsAnti-OSPOlder childrenPrevent choleraIgG antibody responsesYoung childrenB subunitVaccine seriesSignificant IgAIgM responseWhole-cellOlder vaccineesCholera toxinIgAVaccineIgG