Improved Insulin Sensitivity in Patients with Type I Diabetes Mellitus After CSII
Simonson D, Tamborlane W, Sherwin R, Smith J, DeFronzo R, Group T. Improved Insulin Sensitivity in Patients with Type I Diabetes Mellitus After CSII. Diabetes 1985, 34: 80-86. PMID: 3894130, DOI: 10.2337/diab.34.3.s80.Peer-Reviewed Original ResearchConceptsContinuous subcutaneous insulin infusionGlucose metabolismDiabetic patientsControl subjectsTissue sensitivityAge-matched control subjectsEuglycemic insulin clamp techniqueInsulin-mediated glucose utilizationInsulin clamp techniqueSubcutaneous insulin infusionPlasma glucose concentrationHepatic glucose productionInsulin-stimulated glucose uptakeType IIDDM patientsGlycemic controlInsulin infusionInsulin sensitivityImpaired responseInsulin administrationPeripheral tissuesPatientsClamp techniqueGlucose utilizationMetabolic correction