2016
Two-year outcomes after percutaneous coronary intervention of calcified lesions with drug-eluting stents
Généreux P, Redfors B, Witzenbichler B, Arsenault MP, Weisz G, Stuckey TD, Rinaldi MJ, Neumann FJ, Metzger D, Henry TD, Cox DA, Duffy PL, Mazzaferri EL, Francese DP, Marquis-Gravel G, Mintz GS, Kirtane AJ, Maehara A, Mehran R, Stone GW. Two-year outcomes after percutaneous coronary intervention of calcified lesions with drug-eluting stents. International Journal Of Cardiology 2016, 231: 61-67. PMID: 28040289, DOI: 10.1016/j.ijcard.2016.12.150.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionDrug-eluting stentsPlatelet reactivityCoronary interventionIndependent predictorsDES PCILow residual platelet reactivityMajor adverse cardiac eventsSuccessful percutaneous coronary interventionContemporary percutaneous coronary interventionMultivariable logistic regression analysisCox proportional hazards modelDES generationADAPT-DES studyResidual platelet reactivityTarget lesion calcificationAdverse cardiac eventsPeripheral artery diseaseTwo-Year OutcomesKaplan-Meier curvesInsulin-treated diabetesCoronary arterial calcificationProportional hazards modelLogistic regression analysisAssociation of calcification
2015
Reasonable incomplete revascularisation after percutaneous coronary intervention: the SYNTAX Revascularisation Index.
Généreux P, Campos CM, Yadav M, Palmerini T, Caixeta A, Xu K, Francese DP, Dangas GD, Mehran R, Leon MB, Serruys PW, Stone GW. Reasonable incomplete revascularisation after percutaneous coronary intervention: the SYNTAX Revascularisation Index. EuroIntervention 2015, 11: 634-42. PMID: 25308300, DOI: 10.4244/eijy14m10_05.Peer-Reviewed Original ResearchMeSH KeywordsAgedArea Under CurveChi-Square DistributionCoronary AngiographyCoronary Artery DiseaseDecision Support TechniquesFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPercutaneous Coronary InterventionPredictive Value of TestsProportional Hazards ModelsProspective StudiesRisk AssessmentRisk FactorsROC CurveTime FactorsTreatment OutcomeConceptsResidual SYNTAX scorePercutaneous coronary interventionBaseline SYNTAX scoreOne-year mortalityCoronary artery diseaseCAD burdenIncomplete revascularisationSYNTAX scoreCoronary interventionOne-year adverse outcomesResidual coronary artery diseaseNew prognostic instrumentPrediction of deathAngiograms of patientsBetter prognostic accuracyDegree of revascularisationACUITY trialArtery diseaseIndependent predictorsMultivariable analysisAdverse outcomesWorse outcomesPrognostic accuracyPrognostic instrumentPatients
2014
Clinical profile and impact of family history of premature coronary artery disease on clinical outcomes of patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction: analysis from the HORIZONS-AMI Trial
Ertelt K, Généreux P, Mintz GS, Brener SJ, Kirtane AJ, McAndrew TC, Francese DP, Ben-Yehuda O, Mehran R, Stone GW. Clinical profile and impact of family history of premature coronary artery disease on clinical outcomes of patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction: analysis from the HORIZONS-AMI Trial. Cardiovascular Revascularization Medicine 2014, 15: 375-380. PMID: 25288517, DOI: 10.1016/j.carrev.2014.09.002.Peer-Reviewed Original ResearchConceptsPremature coronary artery diseaseST-elevation myocardial infarctionPrimary percutaneous coronary interventionCoronary artery diseaseHORIZONS-AMI trialPercutaneous coronary interventionFamily historyCoronary interventionArtery diseaseIndependent predictorsClinical outcomesClinical profileMyocardial infarctionFinal TIMI 3 flowMyocardial blush grade 2Less diabetes mellitusTIMI 3 flowFuture cardiovascular eventsPrognosis of patientsShorter symptom onsetMore dyslipidemiaCardiovascular eventsCurrent smokersSymptom onsetDiabetes mellitus