1996
CD34: Structure, Biology, and Clinical Utility
Krause D, Fackler M, Civin C, May W. CD34: Structure, Biology, and Clinical Utility. Blood 1996, 87: 1-13. PMID: 8547630, DOI: 10.1182/blood.v87.1.1.1.Peer-Reviewed Original ResearchAcute DiseaseAmino Acid SequenceAnimalsAntibodies, MonoclonalAntigens, CD34Antigens, NeoplasmBiomarkersCell AdhesionEndothelium, VascularFibroblastsGene Expression RegulationGenesHematopoietic Stem CellsHumansLeukemia, MyeloidMiceMolecular Sequence DataOrgan SpecificityProtein ConformationRNA Splicing
1995
Full-Length But Not Truncated CD34 Inhibits Hematopoietic Ceil Differentiation of Ml Cells
Fackler M, Krause D, Smith O, Civin C, May W. Full-Length But Not Truncated CD34 Inhibits Hematopoietic Ceil Differentiation of Ml Cells. Blood 1995, 85: 3040-3047. PMID: 7538813, DOI: 10.1182/blood.v85.11.3040.bloodjournal85113040.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAnimalsAntigens, CDAntigens, CD34Base SequenceCell DifferentiationGene Expression Regulation, LeukemicGrowth InhibitorsHematopoietic Stem CellsInterleukin-6Leukemia Inhibitory FactorLeukemia, MyeloidLymphokinesMacrophagesMiceMolecular Sequence DataPeptide FragmentsPhagocytosisRecombinant Fusion ProteinsTumor Cells, CulturedConceptsFull-length CD34Developmental stage-specific mannerM1 myeloid leukemia cellsTerminal myeloid differentiationMurine hematopoietic stemStage-specific mannerProgenitor cellsHematopoietic cell differentiationCD34 proteinNegative regulatory roleCytoplasmic tail domainMurine M1 myeloid leukemia cellsStem/progenitor cellsArrest phenotypeFunction of CD34Tail domainTerminal differentiationCell differentiationRegulatory roleMyeloid differentiationHematopoietic stemDomain regionLeukemia inhibitory factorHematopoietic cellsMyeloid leukemia cells