Coupling mechanical tension and GTPase signaling to generate cell and tissue dynamics
Zmurchok C, Bhaskar D, Edelstein-Keshet L. Coupling mechanical tension and GTPase signaling to generate cell and tissue dynamics. Physical Biology 2018, 15: 046004. PMID: 29473547, DOI: 10.1088/1478-3975/aab1c0.Peer-Reviewed Original ResearchPolarization and migration in the zebrafish posterior lateral line system
Knutsdottir H, Zmurchok C, Bhaskar D, Palsson E, Nogare D, Chitnis A, Edelstein-Keshet L. Polarization and migration in the zebrafish posterior lateral line system. PLOS Computational Biology 2017, 13: e1005451. PMID: 28369079, PMCID: PMC5393887, DOI: 10.1371/journal.pcbi.1005451.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBody PatterningCell MovementCell PolarityComputational BiologyModels, BiologicalZebrafishConceptsPosterior lateral line primordiumZebrafish posterior lateral line systemCell-cell adhesionLateral line primordiumCollective cell migrationPosterior lateral line systemCell-based simulationsMutant phenotypeZebrafish embryosCell divisionFGF ligandsLateral line systemCell migrationTrailing cellsSensory structuresObserved motilityChemotaxisCellsImportant roleCXCL12aPrimordiaAdhesionEmbryosMigrationPhenotype