2020
Tantrum Tool: Development and Open Pilot Study of Online Parent Training for Irritability and Disruptive Behavior
Diaz-Stransky A, Rowley S, Zecher E, Grodberg D, Sukhodolsky DG. Tantrum Tool: Development and Open Pilot Study of Online Parent Training for Irritability and Disruptive Behavior. Journal Of Child And Adolescent Psychopharmacology 2020, 30: 558-566. PMID: 33035067, PMCID: PMC7699014, DOI: 10.1089/cap.2020.0089.Peer-Reviewed Original ResearchConceptsOpen pilot studyAffective Reactivity IndexOpen trialPilot studyFirst-line treatmentSecondary outcome measuresDisruptive Behavior Rating ScaleYoung childrenDisruptive behaviorSignificant reductionDisruptive behavior disordersClinical effectsParent management training interventionOutcome measuresEffective treatmentTreatment retentionBehavior disorderClinical settingParent management trainingPrimary caregiversMeaningful reductionRating ScaleIrritability scoresLimited service availabilityParent training programAssessing Irritability in Children with Autism Spectrum Disorder Using the Affective Reactivity Index
Kalvin CB, Gladstone TR, Jordan R, Rowley S, Marsh CL, Ibrahim K, Sukhodolsky DG. Assessing Irritability in Children with Autism Spectrum Disorder Using the Affective Reactivity Index. Journal Of Autism And Developmental Disorders 2020, 51: 1496-1507. PMID: 32734421, PMCID: PMC7855357, DOI: 10.1007/s10803-020-04627-9.Peer-Reviewed Original Research
2018
An Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder
Lewis AS, van Schalkwyk GI, Lopez MO, Volkmar FR, Picciotto MR, Sukhodolsky DG. An Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder. Journal Of Autism And Developmental Disorders 2018, 48: 2748-2757. PMID: 29536216, PMCID: PMC6394231, DOI: 10.1007/s10803-018-3536-7.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSpectrum disorderTransdermal nicotineDouble-blind crossover trialAggressive behaviorPreliminary efficacyAggressive symptomsSleep ratingsAggressionSubscale changesNicotinic acetylcholine receptorsNAChR agonistsPrimary outcomeNicotine treatmentCrossover trialExploratory trialΑ7 nAChRsAcetylcholine receptorsNicotineAdultsDisordersPlaceboNAChRsFurther investigationTrials
2016
Behavioral Interventions for Anger, Irritability, and Aggression in Children and Adolescents
Sukhodolsky DG, Smith SD, McCauley SA, Ibrahim K, Piasecka JB. Behavioral Interventions for Anger, Irritability, and Aggression in Children and Adolescents. Journal Of Child And Adolescent Psychopharmacology 2016, 26: 58-64. PMID: 26745682, PMCID: PMC4808268, DOI: 10.1089/cap.2015.0120.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyParent management trainingAnger/irritabilityTransdiagnostic approachBehavioral interventionsDisruptive behaviorAggressive behaviorChild disruptive behaviorCallous-unemotional traitsDisruptive behavior disordersTreatment of irritabilityEmotion regulationAversive patternFamily interactionsBehavioral problemsAngerMental health referralsAggressionManagement trainingBehavior disorderMood disordersTreatment targetsIrritabilityChildrenPsychiatric diagnosis