2021
Electrophysiological signatures of inhibitory control in children with Tourette syndrome and attention-deficit/hyperactivity disorder
Morand-Beaulieu S, Smith SD, Ibrahim K, Wu J, Leckman JF, Crowley MJ, Sukhodolsky DG. Electrophysiological signatures of inhibitory control in children with Tourette syndrome and attention-deficit/hyperactivity disorder. Cortex 2021, 147: 157-168. PMID: 35042055, PMCID: PMC8816877, DOI: 10.1016/j.cortex.2021.12.006.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderGo/NoGo taskFrontal midline theta oscillationsFrontal midline theta powerEvent-related potentialsNoGo taskHyperactivity disorderInhibitory controlTheta powerTheta oscillationsP300 latencyInhibitory control abilitiesDense-array EEG recordingsDistinct electrophysiological profileTourette syndromeNeural underpinningsElectrophysiological correlatesTask performanceBehavioral performanceElectrophysiological signaturesP300 componentBrain activityN200Control abilityTaskOrganizational skills training for children with ADHD: study protocol for a randomized, controlled trial
Bikic A, Dalsgaard S, Olsen KD, Sukhodolsky DG. Organizational skills training for children with ADHD: study protocol for a randomized, controlled trial. Trials 2021, 22: 752. PMID: 34715906, PMCID: PMC8556963, DOI: 10.1186/s13063-021-05499-9.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAttentionAttention Deficit Disorder with HyperactivityBehavior TherapyChildCognitionHumansParentsRandomized Controlled Trials as TopicTreatment OutcomeConceptsAttention deficit hyperactivity disorderOrganizational skills trainingOrganizational skillsPoor organizational skillsWeekly therapy sessionsUsual control groupInattention ratingsSustained attentionSkill deficitsParent ratingsHyperactivity disorderLives of childrenNeurocognitive testsSchool functioningSkills trainingGroup formatCognitive functionBehavioral interventionsSkills ScalePresent deficitsAcademic performanceWeekly sessionsInattentionTherapy sessionsTreatment response
2019
Effects of Integrated Brain, Body, and Social (IBBS) intervention on ERP measures of attentional control in children with ADHD
Smith SD, Crowley MJ, Ferrey A, Ramsey K, Wexler BE, Leckman JF, Sukhodolsky DG. Effects of Integrated Brain, Body, and Social (IBBS) intervention on ERP measures of attentional control in children with ADHD. Psychiatry Research 2019, 278: 248-257. PMID: 31233935, PMCID: PMC6637759, DOI: 10.1016/j.psychres.2019.06.021.Peer-Reviewed Original ResearchMeSH KeywordsAttentionAttention Deficit Disorder with HyperactivityBehavior TherapyBrainChildCognitive Behavioral TherapyCombined Modality TherapyElectroencephalographyEvoked PotentialsExerciseExercise TherapyFemaleHumansMalePilot ProjectsReaction TimeTreatment OutcomeConceptsBehavioral measuresAttentional controlIntegrated brainGo/No-Go taskGo-P3 latencySlower reaction timesSocial interventionsRobust treatment effectAttentional systemADHD groupERP measuresDifference waveP3 latencyBrain activityADHDTAU groupEEG proceduresHealthy controlsHC groupReaction timeReplication purposesERPTreatment effectsChildrenSecondary goal
2017
Moderators and predictors of response to behavior therapy for tics in Tourette syndrome
Sukhodolsky DG, Woods DW, Piacentini J, Wilhelm S, Peterson AL, Katsovich L, Dziura J, Walkup JT, Scahill L. Moderators and predictors of response to behavior therapy for tics in Tourette syndrome. Neurology 2017, 88: 1029-1036. PMID: 28202705, PMCID: PMC5384839, DOI: 10.1212/wnl.0000000000003710.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAttention Deficit Disorder with HyperactivityBehavior TherapyChildFemaleHumansMaleMiddle AgedOutcome Assessment, Health CarePredictive Value of TestsTicsTourette SyndromeTreatment OutcomeYoung AdultConceptsPredictors of responseChronic tic disorderTic reductionTic disordersPsychiatric disordersYale Global Tic Severity Scale-Total Tic ScoreTic severityTourette syndromeClinical Global Impressions-Improvement scoreCo-occurring psychiatric disordersAnxiety disordersSubgroup of patientsTotal tic scoreMain outcome measuresPredictors of outcomeBehavior therapyComprehensive Behavioral InterventionAttention-deficit/hyperactivity disorderPremonitory urge severityReduction of ticsCo-occurring attention-deficit/hyperactivity disorderGreater tic severityTIC characteristicsTic improvementClinical characteristics
2016
Meta-analysis of organizational skills interventions for children and adolescents with Attention-Deficit/Hyperactivity Disorder
Bikic A, Reichow B, McCauley SA, Ibrahim K, Sukhodolsky DG. Meta-analysis of organizational skills interventions for children and adolescents with Attention-Deficit/Hyperactivity Disorder. Clinical Psychology Review 2016, 52: 108-123. PMID: 28088557, DOI: 10.1016/j.cpr.2016.12.004.Peer-Reviewed Original ResearchAdolescentAttention Deficit Disorder with HyperactivityBehavior TherapyChildHumansParentsTask Performance and AnalysisTime ManagementTreatment OutcomeModerators of Parent Training for Disruptive Behaviors in Young Children with Autism Spectrum Disorder
Lecavalier L, Smith T, Johnson C, Bearss K, Swiezy N, Aman MG, Sukhodolsky DG, Deng Y, Dziura J, Scahill L. Moderators of Parent Training for Disruptive Behaviors in Young Children with Autism Spectrum Disorder. Research On Child And Adolescent Psychopathology 2016, 45: 1235-1245. PMID: 27917460, PMCID: PMC5459681, DOI: 10.1007/s10802-016-0233-x.Peer-Reviewed Original ResearchMeSH KeywordsAnxietyAttention Deficit Disorder with HyperactivityAutism Spectrum DisorderChildChild BehaviorChild, PreschoolComorbidityEducation, NonprofessionalFamily TherapyFemaleHumansMaleProblem BehaviorConceptsHome Situations QuestionnaireAutism spectrum disorderParent education programAttention deficit hyperactivity disorderParent trainingAberrant Behavior Checklist-Irritability subscaleSpectrum disorderClinical Global Impressions-Improvement scaleDisruptive behaviorOppositional defiant disorder symptomsASD symptom severityLow anxiety groupDeficit hyperactivity disorderYoung childrenADHD groupASD severityHyperactivity disorderAnxiety groupDisorder symptomsPotential moderatorsSituations QuestionnaireNoncompliant behaviorAge 3ModeratorSymptom severityA Randomized Controlled Trial of an Integrated Brain, Body, and Social Intervention for Children With ADHD
Smith SD, Vitulano LA, Katsovich L, Li S, Moore C, Li F, Grantz H, Zheng X, Eicher V, Guloksuz S, Zheng Y, Dong J, Sukhodolsky DG, Leckman JF. A Randomized Controlled Trial of an Integrated Brain, Body, and Social Intervention for Children With ADHD. Journal Of Attention Disorders 2016, 24: 780-794. PMID: 27178060, PMCID: PMC5107355, DOI: 10.1177/1087054716647490.Peer-Reviewed Original ResearchMeSH KeywordsAttention Deficit Disorder with HyperactivityBehavior TherapyBrainChildChild, PreschoolHumansMemory, Short-TermTreatment OutcomeConceptsIntegrated brainComputerized cognitive remediation trainingCognitive remediation trainingSocial interventionsBehavior management strategiesRemediation trainingCognitive trainingMemory taskADHD symptomatologyADHD symptomsNeurocognitive testsTeacher ratingsBlinded clinician ratingGeneralized improvementADHDMultiple group comparisonsClinician ratingsMultiple domainsClinical functioningSignificant treatment effectOutcome measuresGroup comparisonsSecondary outcome measuresChildrenRatings
2010
Neuropsychological Functioning in Children With Tourette Syndrome With and Without Attention-Deficit/Hyperactivity Disorder
Sukhodolsky DG, Landeros-Weisenberger A, Scahill L, Leckman JF, Schultz RT. Neuropsychological Functioning in Children With Tourette Syndrome With and Without Attention-Deficit/Hyperactivity Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 2010, 49: 1155-1164.e1. PMID: 20970703, PMCID: PMC2965169, DOI: 10.1016/j.jaac.2010.08.008.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAttention Deficit Disorder with HyperactivityChildFemaleHumansMaleNeuropsychological TestsPsychomotor AgitationPsychomotor PerformanceReactive InhibitionSeverity of Illness IndexTourette SyndromeConceptsAttention-deficit/hyperactivity disorderConnors' Continuous Performance TestVisual-Motor Integration TestVisual-motor integrationContinuous Performance TestNeuropsychological functioningResponse inhibitionHyperactivity disorderCo-occurring attention-deficit/hyperactivity disorderStroop Color-Word Interference TestColor-Word Interference TestBeery Visual-Motor Integration TestAdequate control conditionsSample of childrenFine motor coordinationTourette syndromeNeuropsychological measuresPurdue Pegboard TestHealthy community control subjectsSubtle deficitsNeurobiological mechanismsNeuropsychological deficitsInterference testControl conditionPegboard TestAdverse Effects of Heavy Prenatal Maternal Smoking on Attentional Control in Children With ADHD
Motlagh MG, Sukhodolsky DG, Landeros-Weisenberger A, Katsovich L, Thompson N, Scahill L, King RA, Peterson BS, Schultz RT, Leckman JF. Adverse Effects of Heavy Prenatal Maternal Smoking on Attentional Control in Children With ADHD. Journal Of Attention Disorders 2010, 15: 593-603. PMID: 20616372, PMCID: PMC3974616, DOI: 10.1177/1087054710374576.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAttentionAttention Deficit Disorder with HyperactivityChildFemaleHumansMaleMothersNeuropsychological TestsPregnancyPrenatal Exposure Delayed EffectsReaction TimeRisk FactorsSmokingConceptsConnors' Continuous Performance TestContinuous Performance TestAttentional controlPrenatal maternal smokingStroop Color-Word Interference TestColor-Word Interference TestMaternal smokingVisual-Motor Integration TestRisk factorsBeery Visual-Motor Integration TestReaction time variabilityVisual-motor integrationSlower reaction timesDevelopment of ADHDFine motor coordinationNeuropsychological batteryPurdue Pegboard TestHeavy maternal smokingMaternal cigarette smokingPerinatal risk factorsMaternal psychosocial stressMotor inhibitionNeurobiological basisNeuropsychological deficitsADHD
2008
ADHD Symptoms and Associated Psychopathology in a Community Sample of Adolescents From the European North of Russia
Ruchkin V, Lorberg B, Koposov R, Schwab-Stone M, Sukhodolsky DG. ADHD Symptoms and Associated Psychopathology in a Community Sample of Adolescents From the European North of Russia. Journal Of Attention Disorders 2008, 12: 54-63. PMID: 17712166, DOI: 10.1177/1087054707305169.Peer-Reviewed Original ResearchAdolescentAttention Deficit Disorder with HyperactivityCatchment Area, HealthChildComorbidityEuropeFacultyFemaleHumansMaleMental DisordersObserver VariationResidence CharacteristicsRussiaSeverity of Illness IndexViolence
2007
Parent-Rated Anxiety Symptoms in Children with Pervasive Developmental Disorders: Frequency and Association with Core Autism Symptoms and Cognitive Functioning
Sukhodolsky DG, Scahill L, Gadow KD, Arnold LE, Aman MG, McDougle CJ, McCracken JT, Tierney E, Williams White S, Lecavalier L, Vitiello B. Parent-Rated Anxiety Symptoms in Children with Pervasive Developmental Disorders: Frequency and Association with Core Autism Symptoms and Cognitive Functioning. Research On Child And Adolescent Psychopathology 2007, 36: 117-128. PMID: 17674186, DOI: 10.1007/s10802-007-9165-9.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAggressionAntipsychotic AgentsAnxietyAsperger SyndromeAttention Deficit Disorder with HyperactivityAutistic DisorderCentral Nervous System StimulantsChildChild Development Disorders, PervasiveChild, PreschoolCognition DisordersComorbidityCross-Over StudiesDouble-Blind MethodFemaleHumansIntelligenceLanguage Development DisordersMaleMethylphenidatePersonality AssessmentRandomized Controlled Trials as TopicRisperidoneSocial BehaviorStereotyped BehaviorConceptsPervasive developmental disorderParent-rated anxiety symptomsAnxiety symptomsHigher IQCore symptomsDevelopmental disordersCore autism symptomsAdolescent Symptom InventoryFunctional language useMedication-free childrenSocial anxietyAutism symptomsCognitive functioningParent ratingsSocial reciprocityResultsForty-three percentProblem behaviorAnxiety disordersSymptom InventoryOverall impairmentAnxietyGreater impairmentLanguage useStereotyped behaviorIQThe role of abnormal neural oscillations in the pathophysiology of co-occurring Tourette syndrome and attention-deficit/hyperactivity disorder
Sukhodolsky DG, Leckman JF, Rothenberger A, Scahill L. The role of abnormal neural oscillations in the pathophysiology of co-occurring Tourette syndrome and attention-deficit/hyperactivity disorder. European Child & Adolescent Psychiatry 2007, 16: 51-59. PMID: 17665283, DOI: 10.1007/s00787-007-1007-3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAttention Deficit Disorder with HyperactivityBrainComorbidityHumansMagnetic Resonance ImagingNeuronsPeriodicityPositron-Emission TomographyTourette SyndromeConceptsAttention-deficit/hyperactivity disorderTourette syndromeAbnormal neural oscillationsOscillatory activityHyperactivity disorderAbnormal oscillatory activityThalamo-cortical circuitsSymptoms of ADHDNeural oscillationsNeural oscillatory activityBasal gangliaFunctional abnormalitiesNormal brainThalamocortical regionsThalamocortical oscillationsCortical regionsTransient hyperpolarizationPrefrontal cortexNeural activityNeural communicationPathophysiologyMotor controlSyndromeBrainDisordersDrug and non-drug treatments of children with ADHD and tic disorders
Poncin Y, Sukhodolsky DG, McGuire J, Scahill L. Drug and non-drug treatments of children with ADHD and tic disorders. European Child & Adolescent Psychiatry 2007, 16: 78-88. PMID: 17665286, DOI: 10.1007/s00787-007-1010-8.ChaptersMeSH KeywordsAdrenergic alpha-AgonistsAntidepressive AgentsAttention Deficit Disorder with HyperactivityCentral Nervous System StimulantsChildComorbidityHumansRandomized Controlled Trials as TopicSelective Serotonin Reuptake InhibitorsTic DisordersConceptsAttention deficit hyperactivity disorderTreatment of ADHDTreatment of ticsTic disordersTreatment of childrenStimulant medicationWorsening of ticsNon-pharmacological approachesNon-drug treatmentsChronic tic disorderMinority of childrenDeficit hyperactivity disorderMild ticsSignificant morbiditySchool-aged childrenNovel treatmentsMedicationsLiterature searchPreponderance of evidenceAdverse effectsHyperactivity disorderDisordersMore studiesTreatmentChildren
2005
Characterizing Aggressive and Noncompliant Behaviors in a Children’s Psychiatric Inpatient Setting
Sukhodolsky DG, Cardona L, Martin A. Characterizing Aggressive and Noncompliant Behaviors in a Children’s Psychiatric Inpatient Setting. Child Psychiatry & Human Development 2005, 36: 177-193. PMID: 16228146, DOI: 10.1007/s10578-005-3494-0.Peer-Reviewed Original ResearchAdaptive, Emotional, and Family Functioning of Children With Obsessive-Compulsive Disorder and Comorbid Attention Deficit Hyperactivity Disorder
Sukhodolsky DG, do Rosario-Campos MC, Scahill L, Katsovich L, Pauls DL, Peterson BS, King RA, Lombroso PJ, Findley DB, Leckman JF. Adaptive, Emotional, and Family Functioning of Children With Obsessive-Compulsive Disorder and Comorbid Attention Deficit Hyperactivity Disorder. American Journal Of Psychiatry 2005, 162: 1125-1132. PMID: 15930061, PMCID: PMC2291297, DOI: 10.1176/appi.ajp.162.6.1125.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdolescentAttention Deficit Disorder with HyperactivityChildComorbidityCross-Sectional StudiesDiagnostic and Statistical Manual of Mental DisordersEmotionsFamily HealthFemaleHealth StatusHumansMaleObsessive-Compulsive DisorderPersonality InventoryPsychiatric Status Rating ScalesSurveys and QuestionnairesConceptsAttention deficit hyperactivity disorderObsessive-compulsive disorderComorbid attention deficit hyperactivity disorderDiagnosis of OCDDeficit hyperactivity disorderFamily functioningEmotional adjustmentHyperactivity disorderVineland Adaptive Behavior ScalesSelf-reported anxietyDaily living skillsAdaptive Behavior ScalesAdolescents ages 7Self-reported depressionBest-estimate DSM-IV diagnosesGroup of childrenAdaptive functioningLevel of impairmentChild functioningParent ratingsComparison childrenEmotional functioningComprehensive batteryLiving skillsDSM-IV diagnosisPublic health significance of tic disorders in children and adolescents.
Scahill L, Sukhodolsky DG, Williams SK, Leckman JF. Public health significance of tic disorders in children and adolescents. Advances In Neurology 2005, 96: 240-8. PMID: 16383223.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAttention Deficit Disorder with HyperactivityChildHumansPrevalencePublic HealthResidence CharacteristicsTic DisordersTourette SyndromeConceptsTic disordersPresence of ADHDAbsence of ADHDPublic health significanceCommunity sampleMild ticsPersistent ticsGreater disabilityVocal ticsDaily livingDisruptive behaviorChronic ticsHealth significanceDisordersClinical samplesCommunity surveyChildrenADHDMinimal consequencesMultiple motorsImpairment
2003
Disruptive Behavior in Children With Tourette's Syndrome: Association With ADHD Comorbidity, Tic Severity, and Functional Impairment
SUKHODOLSKY DG, SCAHILL L, ZHANG H, PETERSON BS, KING RA, LOMBROSO PJ, KATSOVICH L, FINDLEY D, LECKMAN JF. Disruptive Behavior in Children With Tourette's Syndrome: Association With ADHD Comorbidity, Tic Severity, and Functional Impairment. Journal Of The American Academy Of Child & Adolescent Psychiatry 2003, 42: 98-105. PMID: 12500082, DOI: 10.1097/00004583-200301000-00016.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAttention Deficit Disorder with HyperactivityCase-Control StudiesChildChild Behavior DisordersComorbidityConnecticutFamily RelationsFemaleHumansMaleMultivariate AnalysisRegression AnalysisSocial AdjustmentTourette SyndromeConceptsAttention-deficit/hyperactivity disorderComorbid attention-deficit/hyperactivity disorderDisruptive behaviorFamily functioningParent ratingsTeacher ratingsDiagnosis of ADHDVineland Adaptive Behavior ScalesDisruptive behavior problemsHierarchical regression analysisAdaptive Behavior ScalesBest-estimate DSM-IV diagnosesUnaffected control childrenTourette syndromeConduct problemsDelinquency scoresHyperactivity disorderADHD comorbidityDelinquent behaviorBehavior problemsDSM-IV diagnosisDependent measuresDiagnostic statusBehavior ScaleFunctional impairment