2017
Reduced anxiety following pivotal response treatment in young children with autism spectrum disorder
Lei J, Sukhodolsky DG, Abdullahi SM, Braconnier ML, Ventola P. Reduced anxiety following pivotal response treatment in young children with autism spectrum disorder. Research In Autism Spectrum Disorders 2017, 43: 1-7. PMID: 29333196, PMCID: PMC5761743, DOI: 10.1016/j.rasd.2017.09.002.Peer-Reviewed Original ResearchPivotal Response TreatmentResponse treatmentAnxiety symptomsAnxiety reductionYoung childrenCo-occurring anxiety symptomsAttention deficit hyperactivity disorderSocial communication skillsAutism symptom severityAdolescent Symptom InventoryAutism spectrum disorderCognitive behavioral therapySignificant anxiety reductionCo-occurring symptomsApplied behavior analysisSchool-aged childrenHyperactivity disorderBehavioral therapySpectrum disorderBehavioral treatmentDisruptive behaviorReduced anxietyAnxiety subscaleSymptom InventoryASD
2016
Brain responses to biological motion predict treatment outcome in young children with autism
Yang D, Pelphrey KA, Sukhodolsky DG, Crowley MJ, Dayan E, Dvornek NC, Venkataraman A, Duncan J, Staib L, Ventola P. Brain responses to biological motion predict treatment outcome in young children with autism. Translational Psychiatry 2016, 6: e948-e948. PMID: 27845779, PMCID: PMC5314125, DOI: 10.1038/tp.2016.213.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderYoung childrenSocial information processingMultivariate pattern analysisMotivation/rewardBiological motionCore deficitComplex neurodevelopmental disorderBrain responsesResponse treatmentSpectrum disorderNeurobiological markersNeural predictorsInformation processingBehavioral interventionsIndividual childrenNeurodevelopmental disordersCurrent findingsNeural circuitsBehavioral deficitsEarly childhoodChildrenUnsuccessful interventionsNeurobiomarkersPattern analysis
2014
Heterogeneity of neural mechanisms of response to pivotal response treatment
Ventola P, Yang DY, Friedman HE, Oosting D, Wolf J, Sukhodolsky DG, Pelphrey KA. Heterogeneity of neural mechanisms of response to pivotal response treatment. Brain Imaging And Behavior 2014, 9: 74-88. PMID: 25370452, PMCID: PMC4993028, DOI: 10.1007/s11682-014-9331-y.Peer-Reviewed Original ResearchConceptsPivotal Response TreatmentPosterior superior temporal sulcusFunctional magnetic resonance imagingAutism spectrum disorderNeural responsesResponse treatmentRight posterior superior temporal sulcusBiological motion perception taskDifferential neural responsesMotion perception taskSuperior temporal sulcusPerception taskTD childrenTemporal sulcusSocial perceptionBrain responsesNeural mechanismsSpectrum disorderSocial communicationNeural vulnerabilityNeural characteristicsNeural systemsVentral striatumReward systemSubcortical regions