2015
Effect of Parent Training vs Parent Education on Behavioral Problems in Children With Autism Spectrum Disorder: A Randomized Clinical Trial
Bearss K, Johnson C, Smith T, Lecavalier L, Swiezy N, Aman M, McAdam DB, Butter E, Stillitano C, Minshawi N, Sukhodolsky DG, Mruzek DW, Turner K, Neal T, Hallett V, Mulick JA, Green B, Handen B, Deng Y, Dziura J, Scahill L. Effect of Parent Training vs Parent Education on Behavioral Problems in Children With Autism Spectrum Disorder: A Randomized Clinical Trial. JAMA 2015, 313: 1524-1533. PMID: 25898050, PMCID: PMC9078140, DOI: 10.1001/jama.2015.3150.Peer-Reviewed Original ResearchConceptsAberrant Behavior Checklist-Irritability subscaleClinical Global Impressions-Improvement scaleParent trainingCo-primary outcomesAutism spectrum disorderClinical Global ImpressionSpectrum disorderDisruptive behaviorParent-reported outcomesParent educationPositive responseClinical improvementSecondary outcomesWeek 24Global ImpressionBlinded cliniciansClinical trialsClinical significanceMAIN OUTCOMEImprovement ScaleGreater severityTreatment assignment
2014
Examination of Aggression and Self-injury in Children with Autism Spectrum Disorders and Serious Behavioral Problems
Carroll D, Hallett V, McDougle CJ, Aman MG, McCracken JT, Tierney E, Arnold LE, Sukhodolsky DG, Lecavalier L, Handen BL, Swiezy N, Johnson C, Bearss K, Vitiello B, Scahill L. Examination of Aggression and Self-injury in Children with Autism Spectrum Disorders and Serious Behavioral Problems. Child And Adolescent Psychiatric Clinics Of North America 2014, 23: 57-72. PMID: 24231167, PMCID: PMC4212264, DOI: 10.1016/j.chc.2013.08.002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAggressionAnalysis of VarianceAntipsychotic AgentsChildChild Development Disorders, PervasiveChild, PreschoolChi-Square DistributionDouble-Blind MethodFemaleHumansIntelligence TestsMaleOutcome Assessment, Health CarePsychiatric Status Rating ScalesRandomized Controlled Trials as TopicRisperidoneSelf-Injurious BehaviorSeverity of Illness IndexConceptsAutism spectrum disorderSubtypes of aggressionSelf-injurious behaviorSpectrum disorderUnderstanding of aggressionSerious behavioral problemsParent interviewsBehavioral problemsSelf-InjuryAggressionStudy findingsChildrenRisperidone trialsChildren 2DisordersIndividualized treatmentPositive responseSubtypesFurther studiesBiological mechanismsHigh rateInterviewsFindingsNarrativesBehavior