2017
Distinct neural bases of disruptive behavior and autism symptom severity in boys with autism spectrum disorder
Yang YJ, Sukhodolsky DG, Lei J, Dayan E, Pelphrey KA, Ventola P. Distinct neural bases of disruptive behavior and autism symptom severity in boys with autism spectrum disorder. Journal Of Neurodevelopmental Disorders 2017, 9: 1. PMID: 28115995, PMCID: PMC5240249, DOI: 10.1186/s11689-017-9183-z.Peer-Reviewed Original ResearchAutism spectrum disorderAutism symptom severityMedial prefrontal cortexAnterior cingulate cortexLow disruptive behaviorCore ASD symptomsBiological motionNeural basisDMN deactivationDisruptive behaviorADHD symptomsASD symptomsSpectrum disorderAnxiety symptomsSymptom severityPosterior superior temporal sulcusBetween-group analysisDefault mode network deactivationDistinct neural basesSuperior temporal sulcusInferior frontal gyrusHigh disruptive behaviorLateral parietal cortexASD participantsNeural underpinnings
2016
Brain responses to biological motion predict treatment outcome in young children with autism
Yang D, Pelphrey KA, Sukhodolsky DG, Crowley MJ, Dayan E, Dvornek NC, Venkataraman A, Duncan J, Staib L, Ventola P. Brain responses to biological motion predict treatment outcome in young children with autism. Translational Psychiatry 2016, 6: e948-e948. PMID: 27845779, PMCID: PMC5314125, DOI: 10.1038/tp.2016.213.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderYoung childrenSocial information processingMultivariate pattern analysisMotivation/rewardBiological motionCore deficitComplex neurodevelopmental disorderBrain responsesResponse treatmentSpectrum disorderNeurobiological markersNeural predictorsInformation processingBehavioral interventionsIndividual childrenNeurodevelopmental disordersCurrent findingsNeural circuitsBehavioral deficitsEarly childhoodChildrenUnsuccessful interventionsNeurobiomarkersPattern analysis