2013
Desmoplastic melanoma: A 12-year experience with sentinel lymph node biopsy
Broer PN, Walker ME, Goldberg C, Buonocore S, Braddock DT, Lazova R, Narayan D, Ariyan S. Desmoplastic melanoma: A 12-year experience with sentinel lymph node biopsy. European Journal Of Surgical Oncology 2013, 39: 681-685. PMID: 23522951, DOI: 10.1016/j.ejso.2013.02.025.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAgedAged, 80 and overBiopsy, NeedleDatabases, FactualDisease-Free SurvivalFemaleFollow-Up StudiesHumansImmunohistochemistryLymph NodesLymphatic MetastasisMaleMelanomaMiddle AgedNeoplasm InvasivenessNeoplasm Recurrence, LocalNeoplasm StagingProspective StudiesRisk AssessmentSentinel Lymph Node BiopsySkin NeoplasmsSurvival AnalysisTreatment OutcomeConceptsSentinel lymph node biopsyDesmoplastic melanomaMixed desmoplastic melanomasPure desmoplastic melanomaNodal metastasisDM subtypesSpecific melanoma subtypesAdditional positive nodesLymph node biopsyHigh incidence rateYale Melanoma UnitPaucity of dataPositive SLNCompletion lymphadenectomyPositive nodesDM groupNodal involvementNode biopsyRegional lymphSentinel lymphLocal recurrenceTransit recurrenceClinical outcomesDistant metastasisMelanoma Unit
2008
Histopathologic and Molecular Aspects of CD56+ Natural Killer/ T-Cell Lymphoma of the Testis
Ornstein DL, Bifulco CB, Braddock DT, Howe JG. Histopathologic and Molecular Aspects of CD56+ Natural Killer/ T-Cell Lymphoma of the Testis. International Journal Of Surgical Pathology 2008, 16: 291-300. PMID: 18573785, DOI: 10.1177/1066896907309687.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorCD56 AntigenCombined Modality TherapyCyclophosphamideDexamethasoneDoxorubicinHumansImmunohistochemistryIn Situ HybridizationKiller Cells, NaturalLymphoma, T-Cell, PeripheralMaleOrchiectomyRNA, ViralTesticular NeoplasmsVincristineConceptsNatural killer/T-cell lymphomaNasal-type natural killer/T-cell lymphomaT-cell lymphomaCytoplasmic CD3Secondary testicular involvementAggressive clinical courseEpstein-Barr virusT-cell antigensT-cell receptor genesB-cell counterpartsComprehensive histopathologicSurface CD56Nasal typeTesticular involvementClinical coursePrimary presentationRare malignancyMonoclonal rearrangementLymphomaYounger ageReceptor geneCD56HistopathologicVariable expressionCD3
2000
Biophysical Characterization of gp41 Aggregates Suggests a Model for the Molecular Mechanism of HIV-associated Neurological Damage and Dementia*
Caffrey M, Braddock D, Louis J, Abu-Asab M, Kingma D, Liotta L, Tsokos M, Tresser N, Pannell L, Watts N, Steven A, Simon M, Stahl S, Wingfield P, Clore G. Biophysical Characterization of gp41 Aggregates Suggests a Model for the Molecular Mechanism of HIV-associated Neurological Damage and Dementia*. Journal Of Biological Chemistry 2000, 275: 19877-19882. PMID: 10747981, DOI: 10.1074/jbc.m001036200.Peer-Reviewed Original ResearchMeSH KeywordsAIDS Dementia ComplexBrainBrain DiseasesChromatography, GelEndopeptidasesExtracellular SpaceHIV Envelope Protein gp41HIV SeropositivityHumansHydrogen-Ion ConcentrationImmunohistochemistryMembrane GlycoproteinsMicroscopy, ElectronProtein BindingProtein Structure, TertiaryRetroviridae ProteinsConceptsNeurological damageBrains of HIVHuman immunodeficiency virusImmunodeficiency virusEnvelope protein gp41HIVBrain tissueDementiaHigh molecular weight formExtracellular aggregatesMolecular weight formsSimian immunodeficiency virus gp41Gp41Molecular mechanismsWeight formsHIV gp41HIV envelope protein gp41Extracellular ectodomainBiochemical methodsDamagePatientsImmunohistochemistryHigh molecular weight aggregatesBrain