2009
Imaging Membrane Potential with Voltage-Sensitive Dyes
Vucinic D, Kosmidis E, Falk C, Cohen L, Loew L, Djurisic M, Zecevic D. Imaging Membrane Potential with Voltage-Sensitive Dyes. 2009, 132-160. DOI: 10.1093/oso/9780195150445.003.0006.Peer-Reviewed Original ResearchMembrane-bound dyeOptical signalSecond harmonic generationVoltage-sensitive dyeDifferent optical propertiesHarmonic generationOptical measurementsOptical propertiesRaman absorptionOptical recordingRise timeSimultaneous measurementAbsorptionFigure 6.1BirefringenceFluorescenceMeasurementsDichroismDyeMolecular probesSignalsSquidKinds of results
2003
Imaging Nervous System Activity with Voltage‐Sensitive Dyes
Zecevic D, Djurisic M, Cohen LB, Antic S, Wachowiak M, Falk CX, Zochowski MR. Imaging Nervous System Activity with Voltage‐Sensitive Dyes. Current Protocols In Neuroscience 2003, 23: 6.17.1-6.17.29. PMID: 18428582, DOI: 10.1002/0471142301.ns0617s23.Peer-Reviewed Original ResearchConceptsNumber of photonsVoltage-sensitive dyeVoltage-sensitive dye measurementsLight sourceShot noiseOptical recordingOptical recording methodSynaptic inputsChoice of dyeSimultaneous measurementNervous system activityAction potential outputAplysia abdominal ganglionLarge signalNoise ratioAbdominal ganglionNervous systemPhotonsDye measurementsOpticsMotor outputSystem activitySensory stimuliMeasurementsVertebrate brain[20] Optical monitoring of neural activity using voltage-sensitive dyes
Djurisic M, Zochowski M, Wachowiak M, Falk CX, Cohen LB, Zecevic D. [20] Optical monitoring of neural activity using voltage-sensitive dyes. Methods In Enzymology 2003, 361: 423-451. PMID: 12624923, DOI: 10.1016/s0076-6879(03)61022-0.Peer-Reviewed Original ResearchConceptsOptical monitoringSecond harmonic generationVoltage-sensitive dyeDifferent optical propertiesMembrane-bound dyeHarmonic generationOptical propertiesOptical measurementsFluorescence resonance energy transferRaman absorptionEnergy transferResonance energy transferSimultaneous measurementAbsorptionBirefringenceMeasurementsDichroismDyeMolecular probesPopulation signalsFluorescenceProbe
1989
Optical recording of membrane potential at the single cell level
Cohen L, Hoepp H, Wu J, Xiao C, Zecevic D, London J. Optical recording of membrane potential at the single cell level. 1989, wd2. DOI: 10.1364/oam.1989.wd2.Peer-Reviewed Original ResearchExcellent time resolutionOptical signalsOptical recordings of membrane potentialGill withdrawal reflexMolecular rotationTime resolutionOptical measurementsRecordings of membrane potentialMembrane potentialNervous systemOptical propertiesAction potential activityPhotodiode arrayOptical recordingActivity of neuronsAbdominal ganglionSimultaneous measurement